Blar i Faculty of Medicine på tittel

Viser treff 4039-4058 av 8832

    • Hypomagnesemia and functional hypoparathyroidism due to novel mutations in the Mg-channel TRPM6 

      Astor, Marianne; Løvås, Kristian; Wolff, Anette Susanne Bøe; Nedrebø, Bjørn Gunnar; Bratland, Eirik; Steen-Johnsen, Jon; Husebye, Eystein Sverre (Peer reviewed; Journal article, 2015)
      Primary hypomagnesemia with secondary hypocalcemia (HSH) is an autosomal recessive disorder characterized by neuromuscular symptoms in infancy due to extremely low levels of serum magnesium and moderate to severe hypocalcemia. ...

    • Hypoxia and hypotension in patients intubated by physician staffed helicopter emergency medical services - a prospective observational multi-centre study 

      Sunde, Geir Arne; Sandberg, Mårten; Lyon, Richard; Fredriksen, Knut; Burns, Brian; Hufthammer, Karl Ove; Røislien, Jo; Sóti, Ákos; Jäntti, Helena; Lockey, David; Heltne, Jon-Kenneth; Sollid, Stephen J. M. (Peer reviewed; Journal article, 2017-07-11)
      Background: The effective treatment of airway compromise in trauma and non-trauma patients is important. Hypoxia and hypotension are predictors of negative patient outcomes and increased mortality, and may be important ...

    • Hypoxia induced responses are reflected in the stromal proteome of breast cancer 

      Kjølle, Silje; Finne, Kenneth; Birkeland, Even; Ardawatia, Vandana; Winge, Ingeborg; Aziz, Sura Mohammed; Knutsvik, Gøril; Wik, Elisabeth; Paulo, Joao A.; Vethe, Heidrun; Kleftogiannis, Dimitrios; Akslen, Lars Andreas (Journal article; Peer reviewed, 2023)
      Cancers are often associated with hypoxia and metabolic reprogramming, resulting in enhanced tumor progression. Here, we aim to study breast cancer hypoxia responses, focusing on secreted proteins from low-grade (luminal-like) ...

    • ‘I am not only beneficial to the community but to the entire country, I am trained as a researcher now’: Developing health research skills in low-income countries 

      Hatløy, Anne; Luthuli, Silondile; John, Vaughn; Haskins, Lyn; Mapumulo, Sphindile; Mutombo, Paulin Beya; Tylleskär, Thorkild; Engebretsen, Ingunn Marie Stadskleiv; Horwood, Christiane; Mapatano, Mala Ali (Journal article, 2021)
      Partnerships between Higher Education Institutions in the global South and North have potential for building capacity in public health research in low-resource countries. We present experiences of partners involved in a ...

    • ‘I can't go to her when I have a problem’: sexuality communication between South African adolescent girls and young women and their mothers 

      Duby, Zoe; Verwoerd, Wilmé; Isaksen, Katja; Jonas, Kim; Maruping, Kealeboga; Dietrich, Janan; Lovette, Ashleigh; Kuo, Caroline; Mathews, Catherine (Journal article; Peer reviewed, 2022)
      Parent–adolescent sexuality communication, the process in which parents and their adolescent children discuss sexuality and sexual and reproductive health, is a key component for adolescents’ protective behaviours. Open ...

    • “I feel good when I drink”—detecting childhood-onset alcohol abuse and dependence in a Ugandan community trial cohort 

      Engebretsen, Ingunn Marie S.; Nalugya, Joyce; Skylstad, Vilde; Ndeezi, Grace; Akol, Angela; Babirye, Juliet Ndimwibo; Nankabirwa, Victoria; Tumwine, James K (Journal article; Peer reviewed, 2020)
      Background Alcohol, substance use, and mental health disorders constitute major public health issues worldwide, including in low income and lower middle-income countries, and early initiation of use is an important predictor ...

    • “I smile, but Without Showing My Teeth”: The Lived Experience of Cleft, Lip, and Palate in Adults 

      Moi, Asgjerd Litleré; Gjengedal, Harald; Lybak, Kari; Vindenes, Hallvard (Journal article; Peer reviewed, 2020)
      Objective: To explore and describe the experience of growing up with unilateral cleft lip and palate (CLP) in adults. Design: Face-to-face interviews. Giorgi’s phenomenological method was used for analysis. Parti ...

    • I tiden etter pasientsikkerhetsprogrammet - En studie om varig endring i spesialisthelsetjenesten 

      Dahler, Anders (Master thesis, 2022-05-31)
      Helsevesenet er i stadig endring, det er derfor svært viktig at helsevesenet evner å gjøre effektive endringer som varer. Det er gjort mye forskning på hva som skal til for at en virksomhet skal endre seg, men det har ...

    • ‘I try not to bother the residents too much’ – the use of capillary blood glucose measurements in nursing homes 

      Andreassen, Lillan Mo; Granas, Anne G; Sølvik, Una Ørvik; Kjome, Reidun Lisbet Skeide (Peer reviewed; Journal article, 2016-02-04)
      Background Capillary blood glucose measurements are regularly used for nursing home residents with diabetes. The usefulness of these measurements relies on clear indications for use, correct measurement techniques, proper ...

    • ‘I wanted to go, but they said wait’: Mothers’ bargaining power and strategies in careseeking for ill newborns in Ethiopia 

      Onarheim, Kristine Husøy; Moland, Karen Marie Ingeborg; Molla, Mitike; Miljeteig, Ingrid (Journal article; Peer reviewed, 2020)
      Introduction To prevent the 2.6 million newborn deaths occurring worldwide every year, health system improvements and changes in care-taker behaviour are necessary. Mothers are commonly assumed to be of particular importance ...

    • Ibuprofen versus mecillinam for uncomplicated cystitis - a randomized controlled trial study protocol 

      Vik, Ingvild; Bollestad, Marianne; Grude, Nils; Bærheim, Anders; Mölstad, Sigvard; Bjerrum, Lars; Lindbæk, Morten (Peer reviewed; Journal article, 2014-12-17)
      Background: Although uncomplicated cystitis is often self-limiting, most such patients will be prescribed antibiotic treatment. We are investigating whether treatment of cystitis with an NSAID is as effective as an antibiotic ...

    • The ideal of equal health revisited: definitions and measures of inequity in health should be better integrated with theories of distributive justice 

      Norheim, Ole Frithjof; Asada, Yukiko (Peer reviewed; Journal article, 2009-11-18)
      The past decade witnessed great progress in research on health inequities. The most widely cited definition of health inequity is, arguably, the one proposed by Whitehead and Dahlgren: "Health inequalities that are avoidable, ...

    • Identification and characterisation of regionally enriched cortex genes in the rat brain 

      Ersland, Kari Merete (Doctoral thesis, 2012-06-14)

    • Identification and characterization of aptameric inhibitors of human neutrophil elastase 

      Malicki, Stanisław; Książek, Mirosław; Sochaj Gregorczyk, Alicja; Kaminska, Marta; Golda, Anna; Chruścicka, Barbara; Mizgalska, Danuta; Potempa, Jan; Marti, Hans Peter; Kozieł, Joanna; Wieczorek, Maciej; Pieczykolan, Jerzy; Mydel, Piotr Mateusz; Dubin, Grzegorz (Journal article; Peer reviewed, 2023)
      Human neutrophil elastase (HNE) plays a pivotal role in innate immunity, inflammation, and tissue remodeling. Aberrant proteolytic activity of HNE contributes to organ destruction in various chronic inflammatory diseases ...

    • Identification and development of small molecule therapies for the treatment of acute myeloid leukaemia 

      Leitch, Calum (Doctoral thesis, 2022-02-11)
      Acute myeloid leukaemia (AML) is a cancer of the bone marrow in which immature myeloid cells exhibit uncontrolled proliferation and failure to differentiate. The global 5-year overall survival rate for AML ranges between ...

    • Identification and functional characterization of a novel susceptibility locus for small vessel vasculitis with MPO-ANCA 

      Dahlqvist, Johanna; Ekman, Diana; Sennblad, Bengt; Kozyrev, Sergey V.; Nordin, Jessika; Karlsson, Åsa; Meadows, Jennifer R. S.; Hellbacher, Erik; Rantapää-Dahlqvist, Solbritt; Berglin, Ewa; Stegmayr, Bernd; Haslund, Bo; Palm, Øyvind; Haukeland, Hilde; Gunnarsson, Iva; Bruchfeld, Annette; Segelmark, Mårten; Ohlsson, Sophie; Mohammad, Aladdin J.; Svärd, Anna Jessica; Pullerits, Rille; Herlitz, Hans; Söderbergh, Annika; Pielberg, Gerli Rosengren; Rosenberg, Lina Hultin; Bianchi, Matteo; Muren, Eva; Omdal, Roald; Jonsson, Roland; Eloranta, Maija-Leena; Rönnblom, Lars; Söderkvist, Peter; Knight, Ann; Eriksson, Per; Lindblad-Toh, Kerstin (Journal article; Peer reviewed, 2021)
      Objective To identify and characterize genetic loci associated with the risk of developing ANCA-associated vasculitides (AAV). Methods Genetic association analyses were performed after Illumina sequencing of 1853 genes ...

    • Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31 

      Permuth-Wey, Jennifer; Lawrenson, K; Shen, HC; Velkova, A; Tyrer, JP; Chen, ZH; Lin, HY; Chen, YA; Tsai, YY; Qu, XT; Ramus, SJ; Karevan, R; Lee, J; Lee, N; Larson, MC; Aben, KK; Anton-Culver, H; Antonenkova, N; Antoniou, AC; Armasu, SM; Bacot, F; Baglietto, L; Bandera, EV; Barnholtz-Sloan, J; Beckmann, MW; Birrer, MJ; Bloom, G; Bogdanova, N; Brinton, LA; Brooks-Wilson, A; Brown, R; Butzow, R; Cai, QY; Campbell, I; Chang-Claude, J; Chanock, S; Chenevix-Trench, G; Cheng, JQ; Cicek, MS; Coetzee, GA; Cook, LS; Couch, FJ; Cramer, DW; Cunningham, JM; Dansonka-Mieszkowska, A; Despierre, E; Doherty, JA; Dork, T; du Bois, A; Durst, M; Easton, DF; Eccles, D; Edwards, R; Ekici, AB; Fasching, PA; Fenstermacher, DA; Flanagan, JM; Garcia-Closas, M; Gentry-Maharaj, A; Giles, GG; Glasspool, RM; Gonzalez-Bosquet, J; Goodman, MT; Gore, M; Gorski, B; Gronwald, J; Hall, P; Halle, Mari Kyllesø; Harter, P; Heitz, F; Hillemanns, P; Hoatlin, M; Hogdall, CK; Hogdall, E; Hosono, S; Jakubowska, A; Jensen, A; Jim, H; Kalli, KR; Karlan, BY; Kaye, SB; Kelemen, LE; Kiemeney, LA; Kikkawa, F; Konecny, GE; Krakstad, Camilla; Kjaer, SK; Kupryjanczyk, J; Lambrechts, D; Lambrechts, S; Lancaster, JM; Le, ND; Leminen, A; Levine, DA; Liang, D; Lim, BK; Lin, J; Lissowska, J; Lu, KH; Lubinski, J; Lurie, G; Massuger, LFAG; Matsuo, K; McGuire, V; McLaughlin, JR; Menon, U; Modugno, F; Moysich, KB; Nakanishi, T; Narod, SA; Nedergaard, L; Ness, RB; Nevanlinna, H; Nickels, S; Noushmehr, H; Odunsi, K; Olson, SH; Orlow, I; Paul, J; Pearce, CL; Pejovic, T; Pelttari, LM; Pike, MC; Poole, EM; Raska, P; Renner, SP; Risch, HA; Rodriguez-Rodriguez, L; Rossing, MA; Rudolph, A; Runnebaum, IB; Rzepecka, IK; Salvesen, Helga Birgitte; Schwaab, I; Severi, G; Shridhar, V; Shu, XO; Shvetsov, YB; Sieh, W; Song, HL; Southey, MC; Spiewankiewicz, B; Stram, D; Sutphen, R; Teo, SH; Terry, KL; Tessier, DC; Thompson, PJ; Tworoger, SS; van Altena, AM; Vergote, I; Vierkant, RA; Vincent, D; Vitonis, AF; Wang-Gohrke, S; Weber, RP; Wentzensen, N; Whittemore, AS; Wik, Elisabeth; Wilkens, LR; Winterhoff, B; Woo, YL; Wu, AH; Xiang, YB; Yang, HP; Zheng, W; Ziogas, A; Zulkifli, F; Phelan, CM; Iversen, E; Schildkraut, JM; Berchuck, A; Fridley, BL; Goode, EL; Pharoah, PDP; Monteiro, ANA; Sellers, TA; Gayther, SA (Peer reviewed; Journal article, 2013-03-27)
      Epithelial ovarian cancer (EOC) has a heritable component that remains to be fully characterized. Most identified common susceptibility variants lie in non-protein-coding sequences. We hypothesized that variants in the 3′ ...

    • Identification of a Blood-Based Protein Biomarker Panel for Lung Cancer Detection 

      El-Khoury, Victoria; Schritz, Anna; Kim, Sang-Yoon; Lesur, Antoine; Sertamo, Katriina; Bernardin, Francois; Petritis, Konstantinos; Pirrotte, Patrick; Selinsky, Cheryl; Whiteaker, Jeffrey R; Zhang, Haizhen; Kennedy, Jacob J; Lin, Chenwei; Lee, Lik Wee; Yan, Ping; Tran, Nhan L; Inge, Landon J; Chalabi, Khaled; Decker, Georges; Bjerkvig, Rolf; Paulovich, Amanda G; Berchem, Guy; Kim, Yeoun Jin (Journal article; Peer reviewed, 2020)
      Lung cancer is the deadliest cancer worldwide, mainly due to its advanced stage at the time of diagnosis. A non-invasive method for its early detection remains mandatory to improve patients’ survival. Plasma levels of 351 ...

    • Identification of a core EMT signature that separates basal-like breast cancers into partial- and post-EMT subtypes 

      Knutsen, Erik; Sajib, Saikat Das; Fiskaa, Tonje; Lorens, James Bradley; Gudjonsson, Thorarinn; Mælandsmo, Gunhild Mari; Johansen, Steinar Daae; Seternes, Ole Morten; Perander, Maria (Journal article; Peer reviewed, 2023)
      Epithelial-mesenchymal transition (EMT) is a cellular plasticity program critical for embryonic development and tissue regeneration, and aberrant EMT is associated with disease including cancer. The high degree of plasticity ...

    • Identification of a novel polymorphism associated with reduced clozapine concentration in schizophrenia patients—a genome-wide association study adjusting for smoking habits 

      Smith, Robert Løvsletten; O’Connell, Kevin; Athanasiu, Lavinia; Djurovic, Srdjan; Kringen, Marianne K.; Andreassen, Ole Andreas; Molden, Espen (Journal article; Peer reviewed, 2020)
      Clozapine (CLZ) is the superior antipsychotic drug for treatment of schizophrenia, but exhibits an extensive interpatient pharmacokinetic variability. Here, we conducted a genome-wide association study (GWAS) of CLZ serum ...