Blar i Faculty of Medicine på tittel
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Alterations in schizophrenia-associated genes can lead to increased power in delta oscillations
(Peer reviewed; Journal article, 2019-02)Genome-wide association studies have implicated many ion channels in schizophrenia pathophysiology. Although the functions of these channels are relatively well characterized by single-cell studies, the contributions of ... -
Alterations of the retinoblastoma gene in metastatic breast cancer
(Peer reviewed; Journal article, 2011-01-21)Germline mutations affecting the retinoblastoma gene (RB1) predispose to inherited retinoblastomas but also other malignancies, including breast cancer. While somatic RB1 mutations have been detected in different malignancies, ... -
Altered development of fetal liver perfusion in pregnancies with pregestational diabetes
(Peer reviewed; Journal article, 2019-03-13)Background: Pregestational diabetes is associated with fetal macrosomia, and umbilical perfusion of the fetal liver has a role in regulating fetal growth. We therefore hypothesized that pregestational diabetes alters fetal ... -
Altered DNA methylation profile in Norwegian patients with Autoimmune Addison’s Disease
(Peer reviewed; Journal article, 2014-03-22)Autoimmune Addison's Disease (AAD) is an endocrine and immunological disease of uncertain pathogenesis resulting from the immune system's destruction of the hormone producing cells of the adrenal cortex. The underlying ... -
Altered Gut Microbial Metabolism of Essential Nutrients in Primary Sclerosing Cholangitis
(Journal article; Peer reviewed, 2021)Background & Aims To influence host and disease phenotype, compositional microbiome changes, which have been demonstrated in patients with primary sclerosing cholangitis (PSC), must be accompanied by functional changes. ... -
Altered immune activation and IL-23 signaling in response to Candida albicans in autoimmune polyendocrine syndrome type 1
(Peer reviewed; Journal article, 2017-09-01)Objective: Autoimmune polyendocrine syndrome type 1 (APS-1) is a rare, childhood onset disease caused by mutations in the autoimmune regulator (AIRE) gene. Chronic mucocutaneous candidiasis (CMC) is one of the three major ... -
Altered levels of cytokines in patients with irritable bowel syndrome are not correlated with fatigue
(Peer reviewed; Journal article, 2018-07-06)Introduction: A considerable number of patients with gastrointestinal complaints attributable to irritable bowel syndrome (IBS) have shown evidence of immune activation. Fatigue is also frequently reported by IBS patients ... -
Altered metabolic landscape in IDH‐mutant gliomas affects phospholipid, energy, and oxidative stress pathways
(Peer reviewed; Journal article, 2017)Heterozygous mutations in NADP‐dependent isocitrate dehydrogenases (IDH) define the large majority of diffuse gliomas and are associated with hypermethylation of DNA and chromatin. The metabolic dysregulations imposed by ... -
Altered phenotype and Stat1 expression in Toll-like receptor 7/8 stimulated monocyte-derived dendritic cells from patients with primary Sjögren's syndrome
(Peer reviewed; Journal article, 2014-08-11)Introduction: Dendritic cells (DC) are the most potent antigen-presenting cells of the immune system, involved in both initiating immune responses and maintaining tolerance. Dysfunctional and via toll-like receptor (TLR) ... -
Altered surface hydrophilicity on copolymer scaffolds stimulate the osteogenic differentiation of human mesenchymal stem cells
(Journal article; Peer reviewed, 2020)Background: Recent studies have suggested that both poly(l-lactide-co-1,5-dioxepan-2-one) (or poly(LLA-co-DXO)) and poly(l-lactide-co-ε-caprolactone) (or poly(LLA-co-CL)) porous scaffolds are good candidates for use as ... -
Altered transcriptome-proteome coupling indicates aberrant proteostasis in Parkinson's disease
(Journal article; Peer reviewed, 2023)Aberrant proteostasis is thought to be implicated in Parkinson’s disease (PD), but patient-derived evidence is scant. We hypothesized that impaired proteostasis is reflected as altered transcriptome-proteome correlation ... -
Alveolar function following extremely preterm birth
(Doctoral thesis, 2022-12-16)Bakgrunn: Ekstremt prematur (EP) fødsel skjer før normal lungeutvikling er fullført, og forstyrrer vekst og differensiering av alveolene. Mindre areal og tykkere membraner i alveolene gjør at lungenes evne til å drive ... -
The ambivalence of losing weight after bariatric surgery
(Peer reviewed; Journal article, 2014-01-29)This study is grounded in a phenomenological lifeworld perspective. It aims at providing rich descriptions of lived experience of the process of losing weight after obesity surgery. Two women participated in in-depth ... -
Amelioration of Severe TNBS Induced Colitis by Novel AP-1 and NF-κB Inhibitors in Rats
(Peer reviewed; Journal article, 2014-01-30)AP-1 and NF-κB inhibitors, namely, DTCM-G and DHMEQ, were investigated in male Wistar rats with severe colitis, induced by TNBS. The animals were randomized into 3 groups. The control group received 0.5 mL of 0.5% of the ... -
Ameloblastic carcinoma of the mandible: A case report and literature review
(Journal article; Peer reviewed, 2020)Ameloblastic carcinoma is a rare malignant odontogenic tumor. Here we present a case of malignant transformation of ameloblastoma into ameloblastic carcinoma over a period of eight years. A cystic lesion in the left mandible ... -
Amniotic band syndrome and limb body wall complex in Europe 1980–2019
(Journal article; Peer reviewed, 2022)Amniotic band syndrome (ABS) and limb body wall complex (LBWC) have an overlapping phenotype of multiple congenital anomalies and their etiology is unknown. We aimed to determine the prevalence of ABS and LBWC in Europe ... -
Amniotic fluid arginine from gestational weeks 13 to 15 is a predictor of birth weight, length, and head circumference
(Peer reviewed; Journal article, 2017-12-14)Arginine is a constituent of proteins and a precursor for polyamines and nitric oxide, and is essential for placentation, angiogenesis, and growth. Maternal plasma arginine concentrations are found to be lower in pregnancies ... -
Amoxicillin did not Reduce Modic Change Oedema in Patients with Chronic Low Back pain - subgroup Analyses of a Randomised Trial (the AIM study)
(Journal article; Peer reviewed, 2022)Study Design. Exploratory subgroup analyses of a randomised trial [Antibiotics in Modic changes (AIM) study]. Objective. The aim was to assess the effect of amoxicillin versus placebo in reducing Modic change (MC) ... -
AMPA receptors at ribbon synapses in the mammalian retina: kinetic models and molecular identity
(Peer reviewed; Journal article, 2018)In chemical synapses, neurotransmitter molecules released from presynaptic vesicles activate populations of postsynaptic receptors that vary in functional properties depending on their subunit composition. Differential ... -
AMPK som regulator av mitokondriell biogenese i en ny reporter-cellemodell
(Master thesis, 2011-08-31)I dette prosjektet studerte vi rollen til den cellulære energisensoren Adenosine Monophosphate Aktivert Protein Kinase (AMPK) ved mitokondriell biogenese i en ny reportercellemodell, HelaNRF1mitoGFP. To kjente AMPK agonister, ...