Blar i Faculty of Medicine på tittel
Viser treff 880-899 av 9104
-
‘Born before arrival’: user and provider perspectives on health facility childbirths in Kapiri Mposhi district, Zambia
(Peer reviewed; Journal article, 2014-09-16)Background: Maternal mortality remains high in sub-Saharan Africa. Health facility intra-partum strategies with skilled birth attendance have been shown to be most effective to address maternal mortality. In Zambia, the ... -
Bortezomib abrogates temozolomide-induced autophagic flux through an ATG5 dependent pathway
(Journal article; Peer reviewed, 2022)Introduction: Glioblastoma (GBM) is invariably resistant to temozolomide (TMZ) chemotherapy. Inhibiting the proteasomal pathway is an emerging strategy to accumulate damaged proteins and inhibit their lysosomal degradation. ... -
Bortezomib administered prior to temozolomide depletes MGMT, chemosensitizes glioblastoma with unmethylated MGMT promoter and prolongs animal survival
(Peer reviewed; Journal article, 2019-08-15)Background Resistance to temozolomide (TMZ) is due in part to enhanced DNA repair mediated by high expression of O6-methyl guanine DNA methyltransferase (MGMT) that is often characterised by unmethylated promoter. Here, ... -
Both the environment and genes are important for concentrations of cadmium and lead in blood
(Peer reviewed; Journal article, 2000-08)Concentrations of cadmium and lead in blood (BCd and BPb, respectively) are traditionally used as biomarkers of environmental exposure. We estimated the influence of genetic factors on these markers in a cohort of 61 ... -
Bounding the average causal effect in Mendelian randomisation studies with multiple proposed instruments: An application to prenatal alcohol exposure and attention deficit hyperactivity disorder
(Journal article; Peer reviewed, 2023)Background As large-scale observational data become more available, caution regarding causal assumptions remains critically important. This may be especially true for Mendelian randomisation (MR), an increasingly popular ... -
Bowel function and quality of life after superior mesenteric nerve plexus transection in right colectomy with D3 extended mesenterectomy
(Peer reviewed; Journal article, 2016)Background: The aim of this study was to ascertain the impact of injury to the superior mesenteric nerve plexus caused by right colectomy with D3 extended mesenterectomy as performed in the prospective multicenter trial: ... -
Bowel Perfusion Measured with Dynamic Contrast-enhanced Ultrasound Predicts Treatment Outcome in Patients with Crohn’s Disease
(Peer reviewed; Journal article, 2014-09-02)Background: To improve management of patients with Crohn's disease (CD), objective measurements of the degree of local inflammation in the gastrointestinal wall are needed. Increased microvessel density and perfusion are ... -
Boys are more stunted than girls in Sub-Saharan Africa: a meta-analysis of 16 demographic and health surveys
(Peer reviewed; Journal article, 2007-04-10)Background: Many studies in sub-Saharan Africa have occasionally reported a higher prevalence of stunting in male children compared to female children. This study examined whether there are systematic sex differences in ... -
Brain amyloid and vascular risk are related to distinct white matter hyperintensity patterns
(Journal article; Peer reviewed, 2020)White matter hyperintensities (WMHs) are associated with vascular risk and Alzheimer’s disease. In this study, we examined relations between WMH load and distribution, amyloid pathology and vascular risk in 339 controls ... -
The brain and brown fat
(Peer reviewed; Journal article, 2015-06-10)Brown adipose tissue (BAT) is a specialized organ responsible for thermogenesis, a process required for maintaining body temperature. BAT is regulated by the sympathetic nervous system (SNS), which activates lipolysis and ... -
Brain atrophy and clinical characteristics predicting SDMT performance in multiple sclerosis: A 10-year follow-up study
(Journal article; Peer reviewed, 2021)Objectives To identify Magnetic Resonance Imaging (MRI), clinical and demographic biomarkers predictive of worsening information processing speed (IPS) as measured by Symbol Digit Modalities Test (SDMT). Methods Demographic, ... -
Brain atrophy and employment in multiple sclerosis patients: a 10-year follow-up study
(Journal article; Peer reviewed, 2020)Background: Multiple sclerosis is often associated with unemployment. The contribution of grey matter atrophy to unemployment is unclear. Objectives: To identify magnetic resonance imaging biomarkers of grey matter and ... -
Brain changes induced by electroconvulsive therapy are broadly distributed
(Peer reviewed; Journal article, 2020-03-01)Background Electroconvulsive therapy (ECT) is associated with volumetric enlargements of corticolimbic brain regions. However, the pattern of whole-brain structural alterations following ECT remains unresolved. Here, we ... -
Brain Computer Interface - Neurophysiology and Experimental Examples
(Master thesis, 2011-07-20)The last century has seen an incredible leap in human medicine, which has led to an increased life expectancy spanning over all age groups. Despite this development of modern medicine some patient groups do not have any ... -
‘Brain fog’, guilt, and gratitude: experiences of symptoms and life changes in older survivors 6 months after hospitalisation for COVID-19
(Journal article; Peer reviewed, 2022)Purpose Several of those who have been infected with COVID-19 suffer from the post-COVID-19 condition months after the acute infection. Little is known about how older survivors have experienced the consequences and how ... -
Brain lateralization, attention and cognitive control in presistent Attention-Deficit/Hyperactivity Disorder
(Doctoral thesis, 2011-12-09)Objective: Divergent brain lateralization and dysfunctional attention and cognitive control may be part of the pathophysiology of ADHD, with the corpus callosum (CC) and the anterior cortex cinguli (ACC) as important ... -
“Brain MR spectroscopy in autism spectrum disorder—the GABA excitatory/inhibitory imbalance theory revisited”
(Peer reviewed; Journal article, 2015-06-22)Magnetic resonance spectroscopy (MRS) from voxels placed in the left anterior cingulate cortex (ACC) was measured from 14 boys with Autism Spectrum Disorder (ASD) and 24 gender and age-matched typically developing (TD) ... -
Brain MRI changes in Parkinson’s disease A cross sectional study
(Doctoral thesis, 2007-11-09)Background: Cognitive impairment is common even in newly diagnosed Parkinson’s disease (PD), and characteristically involves executive and visuospatial functions with deficits also in the memory domain. There is an increased ... -
Brain plasticity after cognitive intervention in patients with mild cognitive impairment (MCI) evaluated by multimodal MR imaging in a randomized, controlled trial.
(Doctoral thesis, 2022-12-16)Hjerneplasitisitet undersøkt hos individer med mild kognitiv svikt etter PC-administrert arbeidsminnetrening, evaluert med multimodal MRI teknikk, en randomisert kontroll studie. Formål: Hovedmålet med studien var å ... -
Brain reactivity during aggressive response in women with premenstrual dysphoric disorder treated with a selective progesterone receptor modulator
(Journal article; Peer reviewed, 2021)Premenstrual dysphoric disorder (PMDD) is a psychiatric condition characterized by late luteal phase affective, cognitive, and physical impairment. The disorder causes significant suffering in about 5% of women in their ...