Blar i Faculty of Medicine på forfatter "Arnell, Per"

Viser treff 1-3 av 3

    • Analysis of host-pathogen gene association networks reveals patient-specific response to streptococcal and polymicrobial necrotising soft tissue infections 

      Jahagirdar, Sanjeevan; Morris, Lorna; Benis, Nirupama; Oppegaard, Oddvar; Svenson, Mattias; Hyldegaard, Ole; Skrede, Steinar; Norrby-Teglund, Anna; Bruun, Trond; Rath, Eivind; Nedrebø, Torbjørn; Arnell, Per; Rosen, Anders; Hedetoft, Morten; Madsen, Martin B.; Svensson, Mattias; Snäll, Johanna; Karlsson, Ylva; Nekludov, Michael; Martins dos Santos, Vitor A. P.; Saccenti, Edoardo (Journal article; Peer reviewed, 2022)
      Background: Necrotising soft tissue infections (NSTIs) are rapidly progressing bacterial infections usually caused by either several pathogens in unison (polymicrobial infections) or Streptococcus pyogenes (mono-microbial ...

    • Interplay between human STING genotype and bacterial NADase activity regulates inter-individual disease variability 

      Movert, Elin; Bolarin, Jaume Salgado; Valfridsson, Christine; Velarde, Jorge; Skrede, Steinar; Nekludov, Michael; Hyldegaard, Ole; Arnell, Per; Svensson, Mattias; Norrby-Teglund, Anna; Cho, Kyu Hong; Elhaik, Eran; Wessels, Michael R.; Råberg, Lars; Carlsson, Fredric (Journal article; Peer reviewed, 2023)
      Variability in disease severity caused by a microbial pathogen is impacted by each infection representing a unique combination of host and pathogen genomes. Here, we show that the outcome of invasive Streptococcus pyogenes ...

    • Neutrophil-derived reactive agents induce a transient SpeB negative phenotype in Streptococcus pyogenes 

      Shumba, Patience; Sura, Thomas; Moll, Kirsten; Chakrakodi, Bhavya; Tölken, Lea A.; Hoßmann, Jörn; Hoff, Katharina J.; Hyldegaard, Ole; Nekludov, Michael; Svensson, Mattias; Arnell, Per; Skrede, Steinar; Norrby-Teglund, Anna; Siemens, Nikolai (Journal article; Peer reviewed, 2023)
      Background Streptococcus pyogenes (group A streptococci; GAS) is the main causative pathogen of monomicrobial necrotizing soft tissue infections (NSTIs). To resist immuno-clearance, GAS adapt their genetic information ...