Blar i Faculty of Medicine på forfatter "Engen, Caroline Benedicte Nitter"
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Exploring the boundaries of precision haemato-oncology : The case of FLT3 length mutated acute myeloid leukaemia
Engen, Caroline Benedicte Nitter (Doctoral thesis, 2020-02-14)This dissertation explores the astounding biological heterogeneity of acute myeloid leukaemia (AML). In three research papers, we study FLT3 length mutated (LM) AML to contribute to the characterisation of genetic diversity ... -
Sex disparity in acute myeloid leukaemia with FLT3 internal tandem duplication mutations: implications for prognosis
Hellesøy, Monica; Engen, Caroline Benedicte Nitter; Grob, Tim; Löwenberg, Bob; Valk, Peter J. M.; Gjertsen, Bjørn T. (Journal article; Peer reviewed, 2021)Incidence, molecular presentation and outcome of acute myeloid leukaemia (AML) are influenced by sex, but little attention has been directed at untangling sex-related molecular and phenotypic differences between female and ... -
Titrating complex mass cytometry panels
Gullaksen, Stein-Erik; Bader, Lucius; Hellesøy, Monica; Sulen, Andre; Fagerholt, Oda Helen Eck; Engen, Caroline Benedicte Nitter; Skavland, Jørn; Gjertsen, Bjørn Tore; Gavasso, Sonia (Peer reviewed; Journal article, 2019-07-13)We describe here a simple and efficient antibody titration approach for cell‐surface markers and intracellular cell signaling targets for mass cytometry. The iterative approach builds upon a well‐characterized backbone ...