Blar i Faculty of Medicine på forfatter "Enserink, Jorrit"

Viser treff 1-4 av 4

    • A cell competition-based small molecule screen identifies a novel compound that induces dual c-Myc depletion and p53 activation 

      Tadele, Dagim Shiferaw; Robertson, Joseph; Crispin, Richard; Herrera, Carmen; Chlubnová, Markéta; Piechaczyk, Laure Isabelle; Ayuda-Duran, Maria del Pilar; Singh, Sachin Kumar; Gedde-Dahl, Tobias; Fløisand, Yngvar; Skavland, Jørn; Wesche, Jørgen; Gjertsen, Bjørn Tore; Enserink, Jorrit (Journal article; Peer reviewed, 2021)
      Breakpoint Cluster Region-Abelson kinase (BCR–Abl) is a driver oncogene that causes chronic myeloid leukemia and a subset of acute lymphoid leukemias. Although tyrosine kinase inhibitors provide an effective treatment for ...

    • Discovery of novel candidates for anti- liposarcoma therapies by medium-scale high-throughput drug screening 

      Grad, Iwona; Hanes, Robert; Ayuda-Durán, Pilar; Kuijjer, Marieke Lydia; Enserink, Jorrit; Meza-Zepeda, Leonardo A; Myklebost, Ola (Journal article; Peer reviewed, 2021)
      Sarcomas are a heterogeneous group of mesenchymal orphan cancers and new treatment alternatives beyond traditional chemotherapeutic regimes are much needed. So far, tumor mutation analysis has not led to significant treatment ...

    • Early response evaluation by single cell signaling profiling in acute myeloid leukemia 

      Tislevoll, Benedicte Sjo; Hellesøy, Monica; Fagerholt, Oda Helen Eck; Gullaksen, Stein-Erik; Srivastava, Aashish; Birkeland, Even; Kleftogiannis, Dimitrios; Ayuda Duran, Pilar; Piechaczyk, Laure Isabelle; Tadele, Dagim Shiferaw; Skavland, Jørn; Panagiotis, Baliakas; Hovland, Randi; Andresen, Vibeke; Seternes, Ole Morten; Tvedt, Tor Henrik Anderson; Aghaeepour, Nima; Gavasso, Sonia; Porkka, Kimmo; Jonassen, Inge; Fløisand, Yngvar; Enserink, Jorrit; Blaser, Nello; Gjertsen, Bjørn Tore (Journal article; Peer reviewed, 2023)
      Aberrant pro-survival signaling is a hallmark of cancer cells, but the response to chemotherapy is poorly understood. In this study, we investigate the initial signaling response to standard induction chemotherapy in a ...

    • Tyrosine kinase inhibitors and interferon‐α increase tunneling nanotube (TNT) formation and cell adhesion in chronic myeloid leukemia (CML) cell lines ( 

      Omsland, Maria; Andresen, Vibeke; Gullaksen, Stein-Erik; Ayuda-Duran, Maria del Pilar; Popa, Mihaela Lucia; Hovland, Randi; Brendehaug, Atle; Enserink, Jorrit; Mc Cormack, Emmet; Gjertsen, Bjørn Tore (Journal article; Peer reviewed, 2020)
      Chronic myeloid leukemia (CML) is a stem cell disease of the bone marrow where mechanisms of inter‐leukemic communication and cell‐to‐cell interactions are proposed to be important for optimal therapy response. Tunneling ...