Blar i Faculty of Medicine på forfatter "Figarska, Sylwia M."

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    • Machine learning based on biomarker profiles identifies distinct subgroups of heart failure with preserved ejection fraction 

      Woolley, Rebecca J.; Ceelen, Daan; Ouwerkerk, Wouter; Tromp, Jasper; Figarska, Sylwia M.; Anker, Stefan D.; Dickstein, Kenneth; Filippatos, Gerasimos; Zannad, Faiez; Marco, Metra; Ng, Leong L.; Samani, Nilesh J.; van Veldhuisen, Dirk J; Lang, Chim C.; Lam, Carolyn S.P.; Voors, Adriaan A. (Journal article; Peer reviewed, 2021)
      Aims The lack of effective therapies for patients with heart failure with preserved ejection fraction (HFpEF) is often ascribed to the heterogeneity of patients with HFpEF. We aimed to identify distinct pathophysiologic ...

    • Pathophysiological pathways related to high plasma growth differentiation factor 15 concentrations in patients with heart failure 

      Ceelen, Daan; Voors, Adriaan A.; Tromp, Jasper; van Veldhuisen, Dirk J.; Dickstein, Kenneth; de Boer, Rudolf A.; Lang, Chim C.; Anker, Stefan D.; Ng, Leong L.; Metra, Marco; Ponikowski, Piotr; Figarska, Sylwia M. (Journal article; Peer reviewed, 2022)
      Aims Elevated concentrations of growth differentiation factor 15 (GDF-15) in patients with heart failure (HF) have been consistently associated with worse clinical outcomes, but what disease mechanisms high GDF-15 ...

    • Systemic oxidative stress associates with disease severity and outcome in patients with new-onset or worsening heart failure 

      de Koning, Marie-Sophie L. Y.; Emmens, Johanna E.; Romero-Hernández, Esteban; Bourgonje, Arno R.; Assa, Solmaz; Figarska, Sylwia M.; Cleland, John G. F.; Samani, Nilesh J.; Ng, Leong L.; Lang, Chim C.; Metra, Marco; Filippatos, Gerasimos S.; van Veldhuisen, Dirk J.; Anker, Stefan D.; Dickstein, Kenneth; Voors, Adriaan A.; Lipsic, Erik; van Goor, Harry; van der Harst, Pim (Journal article; Peer reviewed, 2023)
      Background: Oxidative stress may be a key pathophysiological mediator in the development and progression of heart failure (HF). The role of serum-free thiol concentrations, as a marker of systemic oxidative stress, in HF ...