Browsing Faculty of Medicine by Subject "Annexin A2"
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The native structure of annexin A2 peptides in hydrophilic environment determines their anti-angiogenic effects (Elsevier, 2015-03-13)The progression of aggressive cancer occurs via angiogenesis and metastasis makes these processes important targets for the development of anti-cancer agents. However, recent studies have raised the concern that selective ...Journal article
Post-translational modifications of Annexin A2 are linked to its association with perinuclear nonpolysomal mRNP complexes (Wiley, 2017-02)Various post-translational modifications (PTMs) regulate the localisation and function of the multifunctional protein Annexin A2 (AnxA2). In addition to its various tasks as a cytoskeletal- and membrane-associated protein, ...Journal article
Reactive oxygen species exert opposite effects on Tyr23 phosphorylation of the nuclear and cortical pools of Annexin A2 (The Company of Biologists Ltd., 2015-01-15)Annexin A2 (AnxA2) is a multi-functional and -compartmental protein whose subcellular localisation and functions are tightly regulated by its post-translational modifications. AnxA2 and its Tyr23-phosphorylated form ...Journal article