Blar i Faculty of Medicine på forfatter "Aqrawi, Lara Adnan"
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B cell specificity and pattern in primary Sjögren’s syndrome - Studies in humans and a murine model
Aqrawi, Lara Adnan (Doctoral thesis, 2014-04-30)Sjögren’s syndrome (SS) is a chronic autoimmune disease characterised by focal inflammation of exocrine glands, particularly salivary and lacrimal glands. Here, mononuclear cells, including B cells, infiltrate the glands, ... -
The expression of B & T cell activation markers in children’s tonsils following live attenuated influenza vaccine
Panapasa, Jack A.; Cox, Rebecca Jane; Mohn, Kristin Greve-Isdahl; Aqrawi, Lara Adnan; Brokstad, Karl Albert (Peer reviewed; Journal article, 2015-07-06)Live attenuated influenza vaccines (LAIV) can prevent influenza illness and death in children. The absence of known correlates of protection induced by LAIV requires human studies of underlying mechanisms of vaccine-induced ... -
Expression of NGAL-specific cells and mRNA levels correlate with inflammation in the salivary gland, and its overexpression in the saliva, of patients with primary Sjögren’s syndrome
Aqrawi, Lara Adnan; Jensen, Janicke Cecilie Liaaen; Fromreide, Siren; Galtung, Hilde Kanli; Skarstein, Kathrine (Journal article; Peer reviewed, 2020)Salivary gland involvement is a characteristic feature of primary Sjögren’s syndrome (pSS), where tissue destruction is mediated by infiltrating immune cells, and may be accompanied by the presence of adipose tissue. ... -
Proteomic and histopathological characterisation of sicca subjects and primary Sjögren’s syndrome patients reveals promising tear, saliva and extracellular vesicle disease biomarkers
Aqrawi, Lara Adnan; Galtung, Hilde; Guerreiro, Eduarda; Øvstebø, Reidun; Thiede, Bernd; Utheim, Tor Paaske; Chen, Xiangjun; Utheim, Øygunn Aass; Palm, Øyvind; Skarstein, Kathrine; Jensen, Janicke Liaaen (Peer reviewed; Journal article, 2019-07-31)Background Mononuclear cell infiltration of exocrine glands, production of Ro/SSA and La/SSB autoantibodies, along with oral and ocular dryness, are characteristic features of primary Sjögren’s syndrome (pSS). Non-SS sicca ... -
Pulmonary changes in Norwegian fatal cases of pandemic influenza H1N1 (2009) infection: a morphologic and molecular genetic study
Voltersvik, Pål; Aqrawi, Lara Adnan; Dudman, Susanne Gjeruldsen; Hungnes, Olav; Bostad, Leif; Brokstad, Karl Albert; Cox, Rebecca Jane (Peer reviewed; Journal article, 2016-11)Background: During the pandemic outbreak of the 2009 swine influenza (A(H1N1) pdm09), 32 fatal cases occurred in Norway and 19 of these were included in this study. Objectives: We characterised pulmonary changes in these ...