Blar i Faculty of Medicine på forfatter "Aspevik, Anne"
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B-type natriuretic peptide expression and cardioprotection is regulated by Akt dependent signaling at early reperfusion
Breivik, Lars Ertesvåg; Jensen, Andreas; Guvåg, Steinar; Aarnes, Eva-Katrine; Aspevik, Anne; Helgeland, Erik; Hovland, Siren; Brattelid, Trond; Jonassen, Anne K. (Peer reviewed; Journal article, 2015-04)Exogenously administered B-type natriuretic peptide (BNP) has been shown to offer cardioprotection through activation of particulate guanylyl cyclase (pGC), protein kinase G (PKG) and KATP channel opening. The current study ... -
Insulin and GSK3β-inhibition abrogates the infarct sparing-effect of ischemic postconditioning in ex vivo rat hearts
Helgeland, Erik; Wergeland, Anita; Sandøy, Rune Kringstad; Askeland, Maren Haave; Aspevik, Anne; Breivik, Lars Ertesvåg; Jonassen, Anne K (Peer reviewed; Journal article, 2017)Objectives. Pharmacological treatment of reperfusion injury using insulin and GSK3β inhibition has been shown to be cardioprotective, however, their interaction with the endogenous cardioprotective strategy, ischemic ...