Now showing items 1-2 of 2

    • Excellent response of intramedullary Erdheim-Chester disease to vemurafenib: a case report 

      Tzoulis, Charalampos; Schwarzlmüller, Thomas; Søfteland, Eirik; Neckelmann, Gesche; Biermann, Martin; Haroche, Julien; Straume, Oddbjørn; Gjerde, Ivar Otto; Vintermyr, Olav Karsten (BioMed Central, 2015-04-30)
      Background: Erdheim-Chester disease is a rare histiocytosis characterized by multi-systemic organ involvement. Immune-modulating agents such as interferon-alpha have limited success and the disorder is progressive and ...
      Journal article
    • In vitro treatment of melanoma brain metastasis by simultaneously targeting the MAPK and PI3K signaling pathways 

      Daphu, Inderjit Kaur; Horn, Sindre August; Stieber, Daniel; Varughese, Jobin K.; Spriet, Endy; Dale, Hege Avsnes; Skaftnesmo, Kai Ove; Bjerkvig, Rolf; Thorsen, Frits Alan (MDPI, 2014-05-16)
      Malignant melanoma is the most lethal form of skin cancer, with a high propensity to metastasize to the brain. More than 60% of melanomas have the BRAFV600E mutation, which activates the mitogen-activated protein kinase ...
      Journal article