Browsing Faculty of Medicine by Subject "BRAF"
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(BioMed Central, 2015-04-30)Background: Erdheim-Chester disease is a rare histiocytosis characterized by multi-systemic organ involvement. Immune-modulating agents such as interferon-alpha have limited success and the disorder is progressive and ...Journal article
In vitro treatment of melanoma brain metastasis by simultaneously targeting the MAPK and PI3K signaling pathways (MDPI, 2014-05-16)Malignant melanoma is the most lethal form of skin cancer, with a high propensity to metastasize to the brain. More than 60% of melanomas have the BRAFV600E mutation, which activates the mitogen-activated protein kinase ...Journal article