Blar i Faculty of Medicine på emneord "BRAF"
Viser treff 1-3 av 3
-
Excellent response of intramedullary Erdheim-Chester disease to vemurafenib: a case report
(Peer reviewed; Journal article, 2015-04-30)Background: Erdheim-Chester disease is a rare histiocytosis characterized by multi-systemic organ involvement. Immune-modulating agents such as interferon-alpha have limited success and the disorder is progressive and ... -
In vitro treatment of melanoma brain metastasis by simultaneously targeting the MAPK and PI3K signaling pathways
(Peer reviewed; Journal article, 2014-05-16)Malignant melanoma is the most lethal form of skin cancer, with a high propensity to metastasize to the brain. More than 60% of melanomas have the BRAFV600E mutation, which activates the mitogen-activated protein kinase ... -
Total circulating cell-free DNA as a prognostic biomarker in metastatic colorectal cancer before first-line oxaliplatin-based chemotherapy
(Peer reviewed; Journal article, 2019-05-02)Background: Metastatic colorectal cancer (mCRC) is a heterogeneous disease where prognosis is dependent both on tumor biology and host factors. Total circulating cell-free DNA (cfDNA) has shown to harbor prognostic information ...