Blar i Faculty of Medicine på forfatter "Blø, Magnus"

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    • AXL targeting by a specific small molecule or monoclonal antibody inhibits renal cell carcinoma progression in an orthotopic mice model 

      Chen, Tony Jialiang; Mydel, Piotr Mateusz; Benedyk-Machaczka, Małgorzata; Kamińska, Marta; Kalucka, Urszula; Blø, Magnus; Furriol, Jessica; Gausdal, Gro; Lorens, James Bradley; Osman, Tarig Al-Hadi; Marti, Hans Peter (Journal article; Peer reviewed, 2021)
      AXL tyrosine kinase activation enhances cancer cell survival, migration, invasiveness, and promotes drug resistance. AXL overexpression is typically detected in a high percentage of renal cell carcinomas (RCCs) and is ...

    • Enhanced gene expression from retroviral vectors 

      Blø, Magnus; Micklem, David R.; Lorens, James B. (Peer reviewed; Journal article, 2008-02-25)
      Background: Retroviruses are widely used to transfer genes to mammalian cells efficiently and stably. However, genetic elements required for high-level gene expression are incompatible with standard systems. The retroviral ...

    • Flow cytometry-based functional selection of RNA interference triggers for efficient epi-allelic analysis of therapeutic targets 

      Micklem, David Robert; Blø, Magnus; Bergström, Petra; Hodneland, Erlend; Tiron, Crina Elena; Høiby, Torill; Gjerdrum, Christine; Hammarsten, Ola; Lorens, James B. (Peer reviewed; Journal article, 2014-06-21)
      Background: The dose-response relationship is a fundamental pharmacological parameter necessary to determine therapeutic thresholds. Epi-allelic hypomorphic analysis using RNA interference (RNAi) can similarly correlate ...