• Alcohol at bedtime induces minor changes in sleep stages and blood gases in stable chronic obstructive pulmonary disease 

      Holmedahl, Nils Henrik; Øverland, Britt; Fondenes, Ove; Ellingsen, Ivar; Hardie, Jon Andrew (Peer reviewed; Journal article, 2014-05-17)
      Purpose/background: The purpose of this study is to explore the effect of a moderate dose of alcohol on sleep architecture and respiration in chronic obstructive pulmonary disease (COPD). Alcohol depresses both hypercapnic ...
    • Antibiotikabehandling ved KOLS-forverring ved Haukeland Universitetssykehus 

      Viggen, Kaja Kvikshaug (Master thesis, 2022-05-20)
    • The association of tidal EFL with exercise performance, exacerbations, and death in COPD 

      Aarli, Bernt Bøgvald; Calverley, Peter M.A.; Jensen, Robert L.; Dellacà, Raffaele; Eagan, Tomas Mikal; Bakke, Per S.; Hardie, Jon Andrew (Peer reviewed; Journal article, 2017-07-26)
      Background: Tidal expiratory flow limitation (EFLT) is frequently found in patients with COPD and can be detected by forced oscillations when within-breath reactance of a single-breath is ≥0.28 kPa·s·L-1. The present study ...
    • Comparing microbiota profiles in induced and spontaneous sputum samples in COPD patients 

      Tangedal, Solveig; Aanerud, Marianne; Grønseth, Rune; Drengenes, Christine; Wiker, Harald G; Bakke, Per S.; Eagan, Tomas Mikal (Peer reviewed; Journal article, 2017-08-29)
      Background: Induced and spontaneous sputum are used to evaluate the airways microbiota. Whether the sputum types can be used interchangeably in microbiota research is unknown. Our aim was to compare microbiota in induced ...
    • Comparison of inflammatory markers in induced and spontaneous sputum in a cohort of COPD patients 

      Tangedal, Solveig; Aanerud, Marianne; Persson, Louise Jeanette Pauline; Brokstad, Karl Albert; Bakke, Per S.; Eagan, Tomas Mikal (Peer reviewed; Journal article, 2014-11-15)
      Background: Sputum induction is a non-invasive method for obtaining measurements of inflammation in the airways. Whether spontaneously sampled sputum can be a valid surrogate is unknown. The aim of this study was to compare ...
    • Cost effectiveness of adding budesonide/formoterol to tiotropium in COPD in four Nordic countries 

      Nielsen, Rune; Kankaanranta, Hannu; Bjermer, Leif; Lange, Peter; Arnetorp, Sofie; Hedegaard, Morten; Stenling, Anna; Mittmann, Nicole (Peer reviewed; Journal article, 2013-11)
      Objective: Assess the cost effectiveness of budesonide/formoterol (BUD/FORM) Turbuhaler®+tiotropium (TIO) HandiHaler® vs. placebo (PBO)+TIO in patients with chronic obstructive pulmonary disease (COPD) eligible for inhaled ...
    • Depresjon, dyspné, lungefunksjonsmål og fenotyper - en eksplorativ studie på søken etter varianter av KOLS 

      Klemmetsby, Margrete (Master thesis, 2009-11-16)
      Dyspnoea and depression are among the novel symptoms in COPD patients, especially in severe stages of the disease. Knowledge on pulmonary function or phenotypic classifying of patients is limited concerning whether presence ...
    • Incidence of utilization- and symptom-defined COPD exacerbations in hospital- and population-recruited patients 

      Erdal, Marta; Johannessen, Ane; Eagan, Tomas Mikal; Bakke, Per S.; Gulsvik, Amund; Grønseth, Rune (Peer reviewed; Journal article, 2016-09)
      Objectives: The objectives of this study were to estimate the impact of recruitment source and outcome definition on the incidence of acute exacerbations of COPD (AECOPD) and explore possible predictors of AECOPD. Patients ...
    • Large-scale external validation and comparison of prognostic models: An application to chronic obstructive pulmonary disease 

      Guerra, Beniamino; Haile, Sarah R.; Lamprecht, Bernd; Ramírez, Ana S.; Martinez-Camblor, Pablo; Kaiser, Bernhard; Alfageme, Inmaculada; Almagro, Pere; Casanova, Ciro; Esteban-González, Cristóbal; Soler-Cataluña, Juan J.; de-Torres, Juan P.; Miravitlles, Marc; Celli, Bartolomé R.; Marin, Jose M.; ter Riet, Gerben; Sobradillo, Patricia; Lange, Peter; Garcia-Aymerich, Judith; Antó, Jósep Maria; Turner, Alice M.; Han, Meilan K.; Langhammer, Arnulf; Leivseth, Linda; Bakke, Per S.; Johannessen, Ane; Oga, Toru; Cosio, Borja; Ancochea-Bermúdez, Julio; Echazarreta, Andrés; Roche, Nicolas; Burgel, Pierre-Régis; Sin, Don D.; Soriano, Joan B.; Puhan, Milo A. (Peer reviewed; Journal article, 2018-03-02)
      Background: External validations and comparisons of prognostic models or scores are a prerequisite for their use in routine clinical care but are lacking in most medical fields including chronic obstructive pulmonary disease ...
    • Lung hyperinflation and functional exercise capacity in patients with COPD - a three-year longitudinal study 

      Aalstad, Linn T.; Hardie, Jon Andrew; Espehaug, Birgitte; Thorsen, Einar; Bakke, Per S.; Eagan, Tomas Mikal; Frisk, Bente (Peer reviewed; Journal article, 2018-12-06)
      Background: Lung hyperinflation contributes to dyspnea, morbidity and mortality in chronic obstructive pulmonary disease (COPD). The inspiratory-to-total lung capacity (IC/TLC) ratio is a measure of lung hyperinflation and ...
    • Participation in research bronchoscopy: a literature review 

      Martinsen, Einar Marius Hjellestad; Leiten, Elise Orvedal; Bakke, Per S.; Eagan, Tomas Mikal; Grønseth, Rune (Peer reviewed; Journal article, 2016-02-03)
      Bronchoscopy is the preferred method for collecting biological samples from the lower airways of subjects in clinical research. However, ensuring participation in clinical research can be challenging when the research ...