Blar i Faculty of Medicine på emneord "Cancer"
Viser treff 1-20 av 36
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Assessment of clinically related outcomes and biomarker analysis for translational integration in colorectal cancer (ACROBATICC): study protocol for a population-based, consecutive cohort of surgically treated colorectal cancers and resected colorectal liver metastasis
(Peer reviewed; Journal article, 2016-06-29)Background: More accurate predictive and prognostic biomarkers for patients with colorectal cancer (CRC) primaries or colorectal liver metastasis (CLM) are needed. Outside clinical trials, the translational integration of ... -
Better health-related quality of life (Mental component summary), having a higher level of education, and being less than 75 years of age are predictors of hospital admission among cognitively intact nursing home residents: A 5-year follow-up study
(Peer reviewed; Journal article, 2016-03-07)Objective: To study whether health-related quality of life (HRQOL), activities of daily living (ADL), and anxiety and depression symptoms affect the risk of hospital admission and potential interactions with having a cancer ... -
The biology of aging and cancer: A brief overview of shared and divergent molecular hallmarks
(Peer reviewed; Journal article, 2017-10)Aging is the inevitable time-dependent decline in physiological organ function and is a major risk factor for cancer development. Due to advances in health care, hygiene control and food availability, life expectancy is ... -
Cancer epigenetics in solid organ tumours: A primer for surgical oncologists
(Peer reviewed; Journal article, 2019-05)Cancer is initiated through both genetic and epigenetic alterations. The end-effect of such changes to the DNA machinery is a set of uncontrolled mechanisms of cell division, invasion and, eventually, metastasis. Epigenetic ... -
Cancer patients’ use of primary care out-of-hours services: a cross-sectional study in Norway
(Peer reviewed; Journal article, 2016)Objective: To investigate how cancer patients in Norway use primary care out-of-hours (OOH) services and describe different contact types and procedures. Design: A retrospective cross-sectional registry study using a billing ... -
Cancer-Associated stroke: The Bergen NORSTROKE Study
(Peer reviewed; Journal article, 2015-10-13)Background: Underlying malignancy can cause ischemic stroke in some patients. Mechanisms include the affection of the coagulation cascade, tumor mucin secretion, infections and nonbacterial endocarditis. The release of ... -
Cleavage of the urokinase receptor (uPAR) on oral cancer cells: Regulation by transforming growth factor - beta1 (TGF-beta1) and potential effects on migration and invasion
(Peer reviewed; Journal article, 2017-05-19)Background: Urokinase plasminogen activator (uPA) receptor (uPAR) is up-regulated at the invasive tumour front of human oral squamous cell carcinoma (OSCC), indicating a role for uPAR in tumour progression. We previously ... -
Comorbid Dementia and Cancer in Residents of Nursing Homes: Secondary Analyses of a Cross-Sectional Study
(Peer reviewed; Journal article, 2018)Background: Life expectancy is increasing continuously, which increases the likelihood of developing dementia or cancer. Both dementia and cancer are serious conditions that give manifold symptoms. The interaction of these ... -
Development and Characterization of an ex vivo Organotypic Non-Small Cell Lung Cancer Model to Study the Effect of Elevated Oxygen Treatment
(Master thesis, 2021-06-01)Lung cancer is a leading cause of cancer-related morbidity and mortality worldwide, and also the cancer-form responsible for most cancer related deaths in Norway. Non-small cell lung cancer (NSCLC) accounts for approximately ... -
Economic independence in survivors of cancer diagnosed at a young age: A Norwegian national cohort study
(Peer reviewed; Journal article, 2016-12)BACKGROUND: The impact of cancer on socioeconomic outcomes is attracting attention as the number of survivors of cancer in young age continues to rise. This study examines economic independence in a national cohort of ... -
The effect of hyperbaric oxygen treatment on malignant progression in different breast cancer models in vivo
(Master thesis, 2016-07-01)Background: Hypoxia is an important feature of most solid tumors and has shown to serve as a mediator for aggressive tumor growth and malignant progression of cancer. A correlation between low oxygen tension in tumors and ... -
The effect of hyperbaric oxygen treatment, alone or in combination with 5-FU, on a MDA-MB-231 human mammary tumor model
(Master thesis, 2012-06-20)Background: Previous studies of hyperbaric oxygen (HBO) treatment on chemically induced and murine breast cancer models have shown promising results. This study was performed to elucidate the effects of HBO on a human ... -
Epithelial-mesenchymal interactions in normal and neoplastic human oral mucosa. A study on in vitro organotypic models
(Doctoral thesis, 2005-04-15)Epithelial-mesenchymal interactions are necessary for the development of oral epithelium during embryogenesis, but adult oral epithelium is also under the influence of mesenchymal tissue in both normal and neoplastic ... -
Establishment of a bioluminescence model for microenvironmentally induced oral carcinogenesis with implications for screening bioengineered scaffolds.
(Peer reviewed; Journal article, 2015)Background: Microenvironmental cues play a major role in head and neck cancer. Biodegradable scaffolds used for bone regeneration might also act as stimulative cues for head and neck cancer. The purpose of this study was ... -
Exploring the anti-leukemic effect of the combination treatment with Valproic acid, Lonidamine and Mycophenolate mofetil in acute myeloid leukemia
(Master thesis, 2015-06-01)An accumulation of immature myeloid progenitor cells at the expense of normal hematopoietic precursors characterizes the aggressive heterogeneous cancer acute myeloid leukemia (AML). It affects the bone marrow and peripheral ... -
Global inequities in precision medicine and molecular cancer research
(Peer reviewed; Journal article, 2018-09-04)Precision medicine based upon molecular testing is heralded as a revolution in how cancer is prevented, diagnosed, and treated. Large efforts across the world aim to conduct comprehensive molecular profiling of disease to ... -
Health-related quality of life among cognitively intact nursing home residents with and without cancer – a 6 year longitudinal study
(Peer reviewed; Journal article, 2017-04-27)Background: Limited information exists regarding the natural development of health-related quality of life (HRQOL) and its determinants among mentally intact nursing home (NH) residents. We aimed to examine HRQOL over time ... -
Impaired lymphatic function accelerates cancer growth
(Peer reviewed; Journal article, 2016-06-13)Increased lymphangiogenesis is a common feature of cancer development and progression, yet the influence of impaired lymphangiogenesis on tumor growth is elusive. C3HBA breast cancer and KHT-1 sarcoma cell lines were ... -
Inhibition of mitochondrial respiration prevents BRAF-mutant melanoma brain metastasis
(Peer reviewed; Journal article, 2019-04-10)Melanoma patients carry a high risk of developing brain metastases, and improvements in survival are still measured in weeks or months. Durable disease control within the brain is impeded by poor drug penetration across ... -
Interferon-γ–induced inflammatory markers and the risk of cancer: The Hordaland Health Study
(Peer reviewed; Journal article, 2014-06-19)Background It has been reported that interferon-γ (IFN-γ)–induced inflammatory markers, such as circulating neopterin and kynurenine-to-tryptophan ratio (KTR), are increased in patients with cancer and are also a predictor ...