Blar i Faculty of Medicine på forfatter "Dusinska, Maria"

Viser treff 1-6 av 6

    • Decitabine potentiates efficacy of doxorubicin in a preclinical trastuzumab-resistant HER2-positive breast cancer models 

      Buociková, Verona; Longhin, Eleonora Marta; Pilalis, Eleftherios; Mastrokalou, Chara; Miklíková, Svetlana; Cihova, Marina; Poturnayova, Alexandra; Mackova, Katarina; Bábelová, Andrea; Trnkova, Lenka; El Yamani, Naouale; Zheng, Congying; Rios-Mondragon, Ivan; Labudova, Martina; Csaderova, Lucia; Kuracinova, Kristina Mikus; Makovicky, Peter; Kučerová, Lucia; Matuskova, Miroslava; Cimpan, Mihaela-Roxana; Dusinska, Maria; Babal, Pavel; Chatziioannou, Aristotelis; Gábelová, Alena; Rundén-Pran, Elise; Smolkova, Bozena (Journal article; Peer reviewed, 2022)
      Acquired drug resistance and metastasis in breast cancer (BC) are coupled with epigenetic deregulation of gene expression. Epigenetic drugs, aiming to reverse these aberrant transcriptional patterns and sensitize cancer ...

    • Decitabine-induced DNA methylation-mediated transcriptomic reprogramming in human breast cancer cell lines; the impact of DCK overexpression 

      Buociková, Verona; Tyciakova, Sylvia; Pilalis, Eleftherios; Mastrokalou, Chara; Urbanova, Maria; Matuskova, Miroslava; Demkova, Lucia; Medova, Veronika; Longhin, Eleonora Marta; Rundén-Pran, Elise; Dusinska, Maria; Rios Mondragon, Ivan; Cimpan, Mihaela-Roxana; Gábelová, Alena; Soltysova, Andrea; Smolkova, Bozena; Chatziioannou, Aristotelis (Journal article; Peer reviewed, 2022)
      Decitabine (DAC), a DNA methyltransferase (DNMT) inhibitor, is tested in combination with conventional anticancer drugs as a treatment option for various solid tumors. Although epigenome modulation provides a promising ...

    • Epigenetics in Breast Cancer Therapy—New Strategies and Future Nanomedicine Perspectives 

      Buociková, Verona; Rios-Mondragon, Ivan; Pilalis, Eleftherios; Chatziioannou, Aristotelis; Miklíková, Svetlana; Mego, Michal; Pajuste, Karlis; Rucins, Martins; El Yamani, Naouale; Longhin, Eleonora Marte; Sobolev, Arkadij; Freixanet, Muriel; Puntes, Victor; Plotniece, Aiva; Dusinska, Maria; Cimpan, Mihaela Roxana; Gábelová, Alena; Smolková, Božena (Journal article; Peer reviewed, 2020-12-03)
      Epigenetic dysregulation has been recognized as a critical factor contributing to the development of resistance against standard chemotherapy and to breast cancer progression via epithelial-to-mesenchymal transition. ...

    • High throughput toxicity screening and intracellular detection of nanomaterials 

      Collins, Andrew Richard; Balasubramanyam, Annangi; Rubio, Laura; Marcos, Ricard; Dorn, Marco; Merker, Carolin; Estrela-Lopis, Irina; Cimpan, Mihaela Roxana; Ibrahim, Mohamed; Cimpan, Emil; Ostermann, Melanie; Sauter, Alexander; El Yamani, Naouale; Shaposhnikov, Sergey; Chevillard, Sylvie; Paget, Vincent; Grall, Romain; Delic, Jozo; Goñi- de-Cerio, Felipe; Suarez-Merino, Blanca; Fessard, Valérie; Hogeveen, Kevin N; Fjellsbø, Lise Maria; Runden Pran, Elise; Brzicova, Tana; Topinka, Jan; João Silva, Maria; Leite, PE; Ribeiro, AR; Granjeiro, JM; Grafström, Roland; Prina-Mello, Adriele; Dusinska, Maria (Peer reviewed; Journal article, 2017-01)
      With the growing numbers of nanomaterials (NMs), there is a great demand for rapid and reliable ways of testing NM safety—preferably using in vitro approaches, to avoid the ethical dilemmas associated with animal research. ...

    • Risk Governance of Emerging Technologies Demonstrated in Terms of its Applicability to Nanomaterials 

      Isigonis, Panagiotis; Afantitis, Antreas; Antunes, Dalila; Bartonova, Alena; Beitollahi, Ali; Bohmer, Nils; Bouman, Evert; Chaudhry, Qasim; Cimpan, Mihaela Roxana; Cimpan, Emil; Doak, Shareen; Dupin, Damien; Fedrigo, Doreen; Fessard, Valérie; Gromelski, Maciej; Gutleb, Arno C.; Halappanavar, Sabina; Hoet, Peter; Jeliazkova, Nina; Jomini, Stéphane; Lindner, Sabine; Linkov, Igor; Longhin, Eleonora Marta; Lynch, Iseult; Malsch, Ineke; Marcomini, Antonio; Mariussen, Espen; Fuente, Jesus M. de la; Melagraki, Georgia; Murphy, Finbarr; Neaves, Michael; Packroff, Rolf; Pfuhler, Stefan; Puzyn, Tomasz; Rahman, Qamar; Pran, Elise Rundén; Semenzin, Elena; Serchi, Tommaso; Steinbach, Christoph; Trump, Benjamin; Vrček, Ivana Vinković; Warheit, David; Wiesner, Mark R.; Willighagen, Egon; Dusinska, Maria (Journal article; Peer reviewed, 2020)
      Nanotechnologies have reached maturity and market penetration that require nano‐specific changes in legislation and harmonization among legislation domains, such as the amendments to REACH for nanomaterials (NMs) which ...

    • A strategy towards the generation of testable adverse outcome pathways for nanomaterials 

      Murugadoss, Sivakumar; Vrcek, Ivana Vinkovic; Pem, Barbara; Jagiello, Karolina; Judzinska, Beata; Sosnowska, Anita; Martens, Marvin; Willighagen, Egon L.; Puzyn, Tomasz; Dusinska, Maria; Cimpan, Mihaela-Roxana; Fessard, Valérie; Hoet, Peter H. (Journal article; Peer reviewed, 2021)
      Manufactured nanomaterials (NMs) are increasingly used in a wide range of industrial applications leading to a constant increase in the market size of nano-enabled products. The increased production and use of NMs are ...