Blar i Faculty of Medicine på emneord "Inflammation"
Viser treff 1-20 av 29
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25-hydroxy-vitamin D concentration is not affected by severe or non-severe pneumonia, or inflammation, in young children
(Peer reviewed; Journal article, 2017-01-17)Poor vitamin D status has been associated with increased risk and severity of respiratory tract infections. Whether or not inflammation and infection affects 25-hydroxy vitamin D (25(OH)D) concentration is controversial ... -
Carbamylation of immunoglobulin abrogates activation of the classical complement pathway
(Peer reviewed; Journal article, 2014-11)Post-translational modifications of proteins significantly affect their structure and function. The carbamylation of positively charged lysine residues to form neutral homoitrulline occurs primarily under inflammatory ... -
A chicken protein hydrolysate exerts anti-atherosclerotic effect beyond plasma cholesterol-lowering activity in Apoe−/− mice
(Peer reviewed; Journal article, 2019-01-13)Chicken protein hydrolysates (CPHs) generated from rest raw materials through enzymatic hydrolysis using Corolase PP or Alcalase were shown to reduce inflammation and stimulate hepatic mitochondrial fatty acid oxidation ... -
Conditioned medium from human bone marrow stromal cells attenuates initial inflammatory reactions in dental pulp tissue
(Peer reviewed; Journal article, 2016-05-04)Aim: To evaluate the effect of MSC-conditioned medium (CM) on the secretion of pro- and anti-inflammatory cytokines from dental pulp cells (hDPC) in vitro, and on the gene expression in vivo after replantation of rat molars. ... -
A critical review of pro-cognitive drug targets in psychosis: convergence on myelination and inflammation
(Peer reviewed; Journal article, 2014-02-04)Antipsychotic drugs have thus far focused on dopaminergic antagonism at the D2 receptors, as counteracting the hyperdopaminergia in nigrostriatal and mesolimbic projections has been considered mandatory for the antipsychotic ... -
Cytokines, adhesion molecules, and matrix metalloproteases as predisposing, diagnostic, and prognostic factors in venous thrombosis
(Peer reviewed; Journal article, 2018-05-22)The inflammatory response is a well-established part of, and a prerequisite for, venous thrombosis. To better understand the pathophysiology of venous thrombosis and to identify improved diagnostic biomarkers, further ... -
The effect of electroconvulsive therapy (ECT) on serum tryptophan metabolites
(Peer reviewed; Journal article, 2019-05-31)Background: Prior studies suggest that activation of the tryptophan catabolism via the kynurenine pathway by proinflammatory cytokines may be involved in the pathophysiology of depression. Electroconvulsive therapy (ECT) ... -
A fish protein hydrolysate alters fatty acid composition in liver and adipose tissue and increases plasma carnitine levels in a mouse model of chronic inflammation
(Peer reviewed; Journal article, 2013-10-07)Background: There is growing evidence that fish protein hydrolysate (FPH) diets affect mitochondrial fatty acid metabolism in animals. The aim of the study was to determine if FPH could influence fatty acid metabolism and ... -
Gene expression response in peripheral blood cells of petroleum workers exposed to sub-ppm benzene levels
(Peer reviewed; Journal article, 2018-10-27)Altered gene expression in pathways relevant to leukaemogenesis, as well as reduced levels of circulating lymphocytes, have been reported in workers that were exposed to benzene concentrations below 1 ppm. In this study, ... -
HIV-infected persons with type 2 diabetes show evidence of endothelial dysfunction and increased inflammation
(Peer reviewed; Journal article, 2017-03-29)Background: Increased incidence of cardiovascular diseases (CVD) in both HIV infection and type 2 diabetes (T2D) compared to the general population has been described. Little is known about the combined effect of HIV ... -
Impact of marine oils in inflammatory bowel disease and psoriatic arthritis. With focus on effects of seal oil and whale oil on joint pain
(Doctoral thesis, 2009-09-25)The Western diet has changed significantly over the last century, e.g. by an increased ratio of omega-6 (n-6) to n-3 polyunsaturated fatty acids (PUFA), particularly due to an increase in the use of vegetable oils like soy ... -
Impact of Pre-Pregnancy BMI on B Vitamin and Inflammatory Status in Early Pregnancy: An Observational Cohort Study
(Peer reviewed; Journal article, 2016-11-30)Maternal nutrition and inflammation have been suggested as mediators in the development of various adverse pregnancy outcomes associated with maternal obesity. We have investigated the relation between pre-pregnancy BMI, ... -
Infrared (810-nm) low-level laser therapy on rat experimental knee inflammation
(Peer reviewed; Journal article, 2011-04-12)Arthritis of the knee is the most common type of joint inflammatory disorder and it is associated with pain and inflammation of the joint capsule. Few studies address the effects of the 810-nm laser in such conditions. ... -
Interferon (IFN)-γ-mediated inflammation and the kynurenine pathway in relation to bone mineral density: the Hordaland Health Study
(Peer reviewed; Journal article, 2014-04-24)The risk of osteoporosis increases in inflammatory disorders. In cell-mediated immune activation, interferon (IFN)-γ stimulates macrophage release of neopterin and increases the activity of indoleamine 2,3-dioxygenase ... -
Interferon gamma (IFN-γ)-mediated inflammation and the kynurenine pathway in relation to risk of hip fractures: The Hordaland Health Study
(Peer reviewed; Journal article, 2014-05-10)Summary The cytokine interferon gamma (IFN-γ) stimulates neopterin release and tryptophan degradation into kynurenines through the kynurenine pathway. High levels of neopterin were associated with increased hip fracture ... -
Interferon-γ–induced inflammatory markers and the risk of cancer: The Hordaland Health Study
(Peer reviewed; Journal article, 2014-06-19)Background It has been reported that interferon-γ (IFN-γ)–induced inflammatory markers, such as circulating neopterin and kynurenine-to-tryptophan ratio (KTR), are increased in patients with cancer and are also a predictor ... -
Markers of vitamin B6 status and metabolism as predictors of incident cancer: The Hordaland Health Study.
(Peer reviewed; Journal article, 2014-11-26)Dietary intake and/or circulating concentrations of vitamin B6 have been associated with risk of cancer, but results are inconsistent and mechanisms uncertain. Pyridoxal 5'-phosphate (PLP) is the most commonly used marker ... -
Neopterin as an effect modifier of the cardiovascular risk predicted by total homocysteine: A prospective 2-cohort study
(Peer reviewed; Journal article, 2017-10)Background: Plasma total homocysteine (tHcy) is related to plasma neopterin, an indicator of interferon‐γ‐mediated immune activation, and both biomarkers positively predict cardiovascular risk. We examined whether the ... -
The neutrophil protein S100A12 is associated with a comprehensive ultrasonographic synovitis score in a longitudinal study of patients with rheumatoid arthritis treated with adalimumab
(Peer reviewed; Journal article, 2014-10-04)Background: The calcium-binding protein S100A12 correlates with measures of disease activity in patients with rheumatoid arthritis (RA). The protein reflects neutrophil activation and the present objective was to explore ... -
The neutrophil protein S100A12 is associated with a comprehensive ultrasonographic synovitis score in a longitudinal study of patients with rheumatoid arthritis treated with adalimumab
(Peer reviewed; Journal article, 2014-10-04)Background. The calcium-binding protein S100A12 correlates with measures of disease activity in patients with rheumatoid arthritis (RA). The protein reflects neutrophil activation and the present objective was to explore ...