• Concise review: Altered versus unaltered amniotic membrane as a substrate for limbal epithelial cells 

      Utheim, Tor Paaske; Utheim, Øygunn Aass; Salvanos, Panagiotis; Jackson, Catherine; Schrader, Stefan; Geerling, Gerd; Sehic, Amer (Peer reviewed; Journal article, 2018-03-23)
      Limbal stem cell deficiency (LSCD) can result from a variety of corneal disorders, including chemical and thermal burns, infections, and autoimmune diseases. The symptoms of LSCD may include irritation, epiphora, blepharospasms, ...
    • High Throughput Screening of Additives Using Factorial Design to Promote Survival of Stored Cultured Epithelial Sheets 

      Reppe, Sjur; Jackson, Catherine; Ringstad, Håkon; Tønseth, Kim Alexander; Bakke, Hege Gilbø; Eidet, Jon Roger; Utheim, Tor Paaske (Peer reviewed; Journal article, 2018-11-18)
      There is a need to optimize storage conditions to preserve cell characteristics during transport of cultured cell sheets from specialized culture units to distant hospitals. In this study, we aimed to explore a method to ...
    • Improvement of storage medium for cultured human retinal pigment epithelial cells using factorial design 

      Pasovic, Lara; Utheim, Tor Paaske; Reppe, Sjur; Khan, Ayyad Ahmad Zartasht; Jackson, Catherine; Thiede, Bernd; Berg, Jens Petter; Messelt, Edvard Berger; Eidet, Jon Roger (Peer reviewed; Journal article, 2018-04-09)
      Storage of human retinal pigment epithelium (hRPE) can contribute to the advancement of cell-based RPE replacement therapies. The present study aimed to improve the quality of stored hRPE cultures by identifying storage ...
    • Simple limbal epithelial transplantation: Current status and future perspectives 

      Jackson, Catherine; Ernø, Ina Myklebust; Ringstad, Håkon; Tønseth, Kim Alexander; Dartt, Darlene Ann; Utheim, Tor Paaske (Peer reviewed; Journal article, 2019-12-04)
      Damage to limbal stem cells as a result of injury or disease can lead to limbal stem cell deficiency (LSCD). This disease is characterized by decreased vision that is often painful and may progress to blindness. Clinical ...
    • Stem cell function is conserved during shortterm storage of cultured epidermal cell sheets at 12˚C 

      Ringstad, Håkon; Reppe, Sjur; Schøyen, Tine Hiorth; Tønseth, Kim Alexander; Utheim, Tor Paaske; Jackson, Catherine (Journal article; Peer reviewed, 2020)
      Transplantation of cultured epidermal cell sheets (CES) can be life-saving for patients with large area burns. CES have also been successfully used to regenerate eye and urethral epithelia in animal models. Short-term ...