Blar i Faculty of Medicine på emneord "Metabolism"
Viser treff 1-5 av 5
-
The 14-3-3 proteins in regulation of cellular metabolism
(Peer reviewed; Journal article, 2011-09)Thirty years ago, it was discovered that 14-3-3 proteins could activate enzymes involved in amino acid metabolism. In the following decades, 14-3-3s have been shown to be involved in many different signaling pathways that ... -
Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas
(Peer reviewed; Journal article, 2015-01)Anti-angiogenic therapy in glioblastoma (GBM) has unfortunately not led to the anticipated improvement in patient prognosis. We here describe how human GBM adapts to bevacizumab treatment at the metabolic level. By performing ... -
Markers of vitamin B6 status and metabolism as predictors of incident cancer: The Hordaland Health Study.
(Peer reviewed; Journal article, 2014-11-26)Dietary intake and/or circulating concentrations of vitamin B6 have been associated with risk of cancer, but results are inconsistent and mechanisms uncertain. Pyridoxal 5'-phosphate (PLP) is the most commonly used marker ... -
Metabolic profiles of placenta in preeclampsia using HR-MAS MRS metabolomics
(Peer reviewed; Journal article, 2015-12)Introduction Preeclampsia is a heterogeneous gestational disease characterized by maternal hypertension and proteinuria, affecting 2–7% of pregnancies. The disorder is initiated by insufficient placental development, but ... -
Serum concentrations of active tamoxifen metabolites predict long-term survival in adjuvantly treated breast cancer patients
(Peer reviewed; Journal article, 2017-11-28)Background: Controversies exist as to whether the genetic polymorphisms of the enzymes responsible for the metabolism of tamoxifen can predict breast cancer outcome in patients using adjuvant tamoxifen. Direct measurement ...