Browsing Faculty of Medicine by Subject "Substrate specificity"
Now showing items 1-2 of 2
Structural and thermodynamic insight into phenylalanine hydroxylase from the human pathogen Legionella pneumophila (ElsevierFederation of European Biochemical Societies, 2013-08-19)Phenylalanine hydroxylase from Legionella pneumophila (lpPAH) has a major functional role in the synthesis of the pigment pyomelanin, which is a potential virulence factor. We present here the crystal structure of lpPAH, ...Journal article
Structural similarities and functional differences clarify evolutionary relationships between tRNA healing enzymes and the myelin enzyme CNPase (BioMed Central, 2017-05-16)Background: Eukaryotic tRNA splicing is an essential process in the transformation of a primary tRNA transcript into a mature functional tRNA molecule. 5′-phosphate ligation involves two steps: a healing reaction ...Journal article