Now showing items 1-3 of 3

    • The Arc of synaptic memory 

      Bramham, Clive R.; Alme, Maria N.; Bittins, Margarethe; Kuipers, Sjoukje D.; Nair, Rajeevkumar R.; Pai, Balagopal; Panja, Debabrata; Schubert, Manja; Soule, Jonathan; Tiron, Adrian; Wibrand, Karin (Springer, 2010)
      The immediate early gene Arc is emerging as a versatile, Wnely tuned system capable of coupling changes in neuronal activity patterns to synaptic plasticity, thereby optimizing information storage in the nervous ...
      Peer reviewedJournal article
    • NMDA receptor-dependent regulation of miRNA expression and association with Argonaute during LTP in vivo 

      Pai, Balagopal; Siripornmongcolchai, Taweeporn; Berentsen, Birgitte; Pakzad, Ashraf; Vieuille, Christel Marie; Pallesen, Ståle; Pajak, Maciej; Simpson, T. Ian; Armstrong, J. Douglas; Wibrand, Karin; Bramham, Clive R. (Frontiers, 2014-01-13)
      microRNAs (miRNAs) are major regulators of protein synthesis in the brain. A major goal is to identify changes in miRNA expression underlying protein synthesis-dependent forms of synaptic plasticity such as long-term ...
      Journal article
    • Widespread promoter methylation of synaptic plasticity genes in long-term potentiation in the adult brain in vivo. 

      Maag, Jesper L.V.; Kaczorowski, Dominik C.; Panja, Debabrata; Peters, Timothy J.; Bramham, Clive R.; Wibrand, Karin; Dinger, Marcel E. (BioMed Central, 2017-03-23)
      Background: DNA methylation is a key modulator of gene expression in mammalian development and cellular differentiation, including neurons. To date, the role of DNA modifications in long-term potentiation (LTP) has not ...
      Journal article