Now showing items 1-5 of 5
Effects of blood contamination and the rostro-caudal gradient on the human cerebrospinal fluid proteome
Over the last years there has been an increased focus on the importance of knowing the effect of pre-analytical influence on the proteomes under study, particularly in the field of biomarker discovery. We present three ...
Limited clinical efficacy of azacitidine in transfusion-dependent, growth factor-resistant, low- and Int-1-risk MDS: Results from the nordic NMDSG08A phase II trial
(Nature Publishing Group, 2014)
This prospective phase II study evaluated the efficacy of azacitidine (Aza)+erythropoietin (Epo) in transfusion-dependent patients with lower-risk myelodysplastic syndrome (MDS). Patients ineligible for or refractory to ...
Effect of withholding breastfeeding on the immune response to a live oral rotavirus vaccine in North Indian infants
Interference from transplacental and breast milk antibodies may impede the performance of oral livevaccines. The effect of breastfeeding on the immunogenicity of Rotarix®, a two-dose oral monova-lent rotavirus vaccine, was ...
Patterns of transmitted HIV drug resistance in Europe vary by risk group
Background: In Europe, a continuous programme (SPREAD) has been in place for ten years to study transmission of drug resistant HIV. We analysed time trends of transmitted drug resistance mutations (TDRM) in relation to the ...
Investigation of complement component C4 copy number variation in human longevity
Genetic factors have been estimated to account for about 25% of the variation in an adult’s life span. The complement component C4 with the isotypes C4A and C4B is an effector protein of the immune system, and differences ...