Now showing items 1-4 of 4
Deficient phosphorylation of stat-1 in leukocytes identifies neutralizing antibodies in multiple sclerosis patients treated with interferon-beta
(Public Library of Science, 2014-02-19)
Background: Anti interferon-beta (IFN-β) neutralizing antibodies (NAb) affect efficacy of treatment of multiple sclerosis patients, but exactly when the detrimental effects of NAbs offset therapeutic efficacy is debated. ...
Employment among patients with multiple sclerosis - A population study
(Public Library of Science, 2014-07-23)
Effects of blood contamination and the rostro-caudal gradient on the human cerebrospinal fluid proteome
Over the last years there has been an increased focus on the importance of knowing the effect of pre-analytical influence on the proteomes under study, particularly in the field of biomarker discovery. We present three ...
Identity-by-descent mapping in a Scandinavian multiple sclerosis cohort
(Nature Publishing Group, 2015)
In an attempt to map chromosomal regions carrying rare gene variants contributing to the risk of multiple sclerosis (MS), we identified segments shared identical-by-descent (IBD) using the software BEAGLE 4.0’s refined IBD ...