Faculty of Medicine: Nye registreringer
Viser treff 1-20 av 8753
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Quantitative analogues to visual spike interpretation in EEG
(Doctoral thesis, 2024-05-03)Bakgrunn: Noen skarpe transienter i EEG er interiktale epileptiforme utladninger (IEU) og representerer en biomarkør for epilepsi. Visuell analyse er den gjeldende gullstandarden for å detektere IEUer. En slik analyse ... -
Maternal physical activity affects yolk sac size and growth in early pregnancy, but girls and boys use different strategies
(Journal article; Peer reviewed, 2023)This longitudinal study investigated the impact of actigraphy-measured maternal physical activity on yolk sac size during early development. The yolk sac, a transient extraembryonic organ, plays a crucial role in embryonic ... -
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Clinical trials, medical treatment and pathomechanisms
(Doctoral thesis, 2024-05-02)Myalgisk encefalomyelitt/kronisk utmattelsessyndrom (ME/CFS) er en underprioritert sykdom som rammer 0,2-0,8 % av befolkningen, med ukjent etiologi, høy symptombelastning, ingen biomarkør, og ingen godkjent effektiv ... -
Longitudinal Transcriptomic Analysis of Human Cortical Spheroids Identifies Axonal Dysregulation in the Prenatal Brain as a Mediator of Genetic Risk for Schizophrenia
(Journal article; Peer reviewed, 2024)Background Schizophrenia (SCZ) has a known neurodevelopmental etiology, but limited access to human prenatal brain tissue hampers the investigation of basic disease mechanisms in early brain development. Here, we elucidate ... -
Suitability of issuing sickness certificates in remote consultations during the COVID-19 pandemic. A mixed method study of GPs' experiences
(Journal article; Peer reviewed, 2024)Objective To explore Norwegian GPs’ experiences with and perceived suitability of issuing sickness certifications in remote consultations during the COVID-19 pandemic. Design We used a mixed methods research design. ... -
Cerebrospinal fluid neurofilament light chain mediates age-associated lower learning and memory in healthy adults
(Journal article; Peer reviewed, 2023)Multiple cognitive domains, including learning, memory, and psychomotor speed, show significant reductions with age. Likewise, several cerebrospinal fluid (CSF) neurodegenerative biomarkers, including total tau (t-tau, a ... -
Single use flexible ureteroscopes: Current status and future directions
(Journal article; Peer reviewed, 2023)Introduction: Single use ureteroscopes are a technological innovation that have become available in the past decade and gained increased popularity. To this end, there are now an increasing number of both benchside and ... -
Tenecteplase, 0.4 mg/kg, in Moderate and Severe Acute Ischemic Stroke: A Pooled Analysis of NOR-TEST and NOR-TEST 2A
(Journal article; Peer reviewed, 2023)Background: The optimal dose of tenecteplase in acute ischemic stroke remains to be defined. We present a pooled analysis of the 2 NOR‐TESTs (Norwegian Tenecteplase Stroke Trials) exploring the efficacy and safety of ... -
Pharmacokinetics of epinephrine during cardiac arrest: A pilot study
(Journal article; Peer reviewed, 2023)Aim of the study: Epinephrine has been recommended for several decades for the treatment of cardiac arrest. However, although this potent medicament has a documented impact on the return of spontaneous circulation, it does ... -
The influence of socio-demographic and clinical factors on sick leave and return to work after open-heart surgery: a nationwide registry-based cohort study
(Journal article; Peer reviewed, 2023)Aims: To estimate sick leave (SL) duration after first-time elective open-heart surgery and identify factors contributing to increased SL. Methods and results: A retrospective nationwide cohort study combined data from ... -
Combining Mass Cytometry Data by CyTOFmerge Reveals Additional Cell Phenotypes in the Heterogeneous Ovarian Cancer Tumor Microenvironment: A Pilot Study
(Journal article; Peer reviewed, 2023-10-23)The prognosis of high-grade serous ovarian carcinoma (HGSOC) is poor, and treatment selection is challenging. A heterogeneous tumor microenvironment (TME) characterizes HGSOC and influences tumor growth, progression, and ... -
Cementing techniques for total knee arthroplasty in Norwegian hospitals; a questionnaire-based study
(Journal article; Peer reviewed, 2023-11-18)Background: Cementing technique in total knee arthroplasty (TKA) may influence implant survival. There is limited knowledge about the results with clinically used techniques. The aim of this study was to investigate ... -
Case report: Seropositive myasthenia gravis complicated by limbic encephalitis positive for antibodies to AMPAR and Lgi1
(Journal article; Peer reviewed, 2023-10-12)Objectives: Autoantibodies to the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) and leucine-rich glioma-inactivated 1 (Lgi1) are associated with autoimmune encephalitis. We described an acetylcholine ... -
Longer-term quality of care, effectiveness, and cost-effectiveness of implementing a model of care for osteoarthritis: A cluster-randomized controlled trial
(Journal article; Peer reviewed, 2024)Objective: To assess the quality of care, effectiveness, and cost-effectiveness over 12 months after implementing a structured model of care for hip and knee osteoarthritis (OA) in primary healthcare as compared to usual ... -
The TP53 Codon 72 Arginine Polymorphism Is Found with Increased TP53 Somatic Mutations in HPV(−) and in an Increased Percentage among HPV(+) Norwegian HNSCC Patients
(Journal article; Peer reviewed, 2023-06-26)Background: Somatic TP53 mutations are frequent in head and neck squamous cell carcinoma (HNSCC) and are important pathogenic factors. Objective: To study TP53 mutations relative to the presence of human papillomavirus ... -
Survival in a consecutive series of 467 glioblastoma patients: Association with prognostic factors and treatment at recurrence at two independent institutions
(Journal article; Peer reviewed, 2023-02-02)Therapy of recurrent glioblastoma (GBM) is challenging due to lack of standard treatment. We investigated physicians’ treatment choice at recurrence and prognostic and predictive factors for survival in GBM patients from ... -
Key terms and definitions in acute porphyrias: Results of an international Delphi consensus led by the European porphyria network
(Journal article; Peer reviewed, 2023)Acute porphyrias are a group of rare inherited disorders causing acute neurovisceral attacks. Many terms used frequently in the literature and clinical practice are ambiguous, which can lead to confusion in the way patients ... -
External validation of SAPS II score reported to the Norwegian Intensive Care and Pandemic Registry (NIPaR)
(Journal article; Peer reviewed, 2023)Background: Simplified Acute Physiology Score II (SAPS II) is a mortality prediction model widely used to compensate for differences between intensive care units (ICU) in benchmarking and research. Accuracy of SAPS II is ... -
The efficacy of integrated hepatitis C virus treatment in relieving fatigue in people who inject drugs: a randomized controlled trial
(Journal article; Peer reviewed, 2023)Background Most people who inject drugs (PWIDs) suffer from severe fatigue, and chronic hepatitis C virus (HCV) infection may play a role in this. However, there is scarce evidence about interventions that alleviate ... -
The surveillance of patients hospitalised with COVID-19 in Norway, February 2020 – May 2022 : Systems comparisons, risk factors and clinical course
(Doctoral thesis, 2024-04-26)Bakgrunn: I Norge ble tre ulike system for overvåking av pasienter innlagt i sykehus med COVID-19 opprettet for å overvåke alvorligheten av pandemien. Ett var en aggregert, manuell innrapportering om belegg ved sykehusene, ...