Now showing items 21-30 of 90
Secreted proteins of mycobacteria and their role during infection
(The University of Bergen, 2012-03-23)
One-third of the world’s population is infected with the causative agent of tuberculosis, Mycobacterium tuberculosis. A fraction of infected individuals have an active form of the disease, while the remainder is able to ...
The effect of influenza virus vaccine formulation : a potential for increased vaccine efficacy
(The University of Bergen, 2005-12-16)
Influenza remains one of the most serious viral diseases in the world, causing substantial morbidity and is responsible for at least one million deaths annually. A vast influenza virus reservoir exists in birds to which ...
Gastric adenocarcinoma: aspects of development and progression in high- and low-risk countries
(The University of Bergen, 2010-03-25)
pRb2/p130 protein expression and RBL2 mutation analysis in Burkitt lymphoma from Uganda
(BioMed Central, 2009-08-19)
Background: The members of the retinoblastoma protein family, pRb, p107 and pRb2 (p130), are central players in controlling the cell cycle. Whereas disturbed function of pRb is commonly seen in human cancers, it is still ...
MicroRNA Alterations and Associated Aberrant DNA Methylation Patterns across Multiple Sample Types in Oral Squamous Cell Carcinoma
(Public Library of Science, 2011-11-22)
Background: MicroRNA (miRNA) expression is broadly altered in cancer, but few studies have investigated miRNA deregulation in oral squamous cell carcinoma (OSCC). Epigenetic mechanisms are involved in the regulation of ...
Functional analysis of tilS homologues in Bacteria and Archaea
(The University of Bergen, 2005-09-09)
Out of all of the microorganisms sequenced so far about one third of the genes have unknown function. Several studies have shown that information on evolutionary relationships between unknown genes can aid in the prediction ...
Ectopic germinal center formation in Sjögren’s syndrome: Significance of lymphoid organization
(The University of Bergen, 2006-06-23)
Sjögren’s syndrom (SS) is an autoimmune, chronic inflammatory disorder predominantly affecting the salivary and lacrimal glands. The overall aim of this study was to determine clinicopathological features in human and ...
Histological type and grade of breast cancer tumors by parity, age at birth, and time since birth: a register-based study in Norway
(BioMed Central, 2010-05-21)
Background Some studies have indicated that reproductive factors affect the risk of histological types of breast cancer differently. The long-term protective effect of a childbirth is preceded by a short-term adverse ...
The Bacterial Preparation OK432 Induces IL-12p70 Secretion in Human Dendritic Cells in a TLR3 Dependent Manner
(Public Library of Science, 2012-02-21)
Dendritic cells (DC) used in therapeutic cancer immunotherapy have to be able to stimulate T cells resulting in an immune response that can efficiently target the cancer cells. One of the critical hurdles has been the lack ...
Comprehensive Analysis of Exported Proteins from Mycobacterium tuberculosis H37Rv
(Wiley-VCH Verlag Berlin, 2007-04-21)
Proteins secreted by Mycobacterium tuberculosis play an essential role in the pathogenesis of tuberculosis. The culture filtrates of M. tuberculosis H37Rv made by Sadamu Nagai (Japan), are considerably enriched for secreted ...