Now showing items 21-30 of 92
Burkitt Lymphoma in Uganda. A study of some biological and epidemiological aspects of endemic Burkitt lymphoma
(The University of Bergen, 2011-08-25)
Biological Characteristics of Stem-Like Cells in Oral Squamous Cell Carcinoma
(The University of Bergen, 2013-06-18)
It has been shown that many solid malignancies, including oral squamous cell carcinoma (OSCC), contain a small population of tumorigenic cells referred to as cancer stem-like cells (CSCs) or tumor initiating cells (TICs). ...
Molecular markers in breast carcinoma. A study with focus on molecular phenotypes, angiogenesis and stem cells in an African population
(The University of Bergen, 2010-09-08)
Tumor necrosis is associated with increased alphav beta3 integrin expression and poor prognosis in nodular cutaneous melanomas
(BioMed Central, 2008-12-05)
Background: Tumor necrosis and apoptotic activity are considered important in cancer progression, but these features have not been much studied in melanomas. Our hypothesis was that rapid growth in cutaneous melanomas of ...
Proliferation, lymph vessel invasion and histologic type as prognostic factors in lymph node negative breast cancer
(The University of Bergen, 2011-12-14)
Breast cancer is a leading cause of cancer mortality among women in the western world, second only to lung cancer. Since the mammography screening program in Norway started in 1995, 70% and more of all new breast cancers ...
The autonomy of different aspects of Sjögren´s syndrome and their treatment in an experimental model: the use of comprehensive biomarker analyses to characterize the disease and the effect of heat-shock proteins in treatment intervention
(The University of Bergen, 2008-06-20)
Sjögren’s syndrome (SS) is a systemic rheumatic disease, in which the salivary and lacrimal glands are the principal targets of a pathological autoimmune reaction. Clinically, SS is manifested by keratoconjunctivitis ...
Benefit from B-Lymphocyte Depletion Using the Anti- CD20 Antibody Rituximab in Chronic Fatigue Syndrome. A Double-Blind and Placebo-Controlled Study
(Public Library of Science, 2011-10-19)
Background: Chronic fatigue syndrome (CFS) is a disease of unknown aetiology. Major CFS symptom relief during cancer chemotherapy in a patient with synchronous CFS and lymphoma spurred a pilot study of B-lymphocyte depletion ...
pRb2/p130 protein expression and RBL2 mutation analysis in Burkitt lymphoma from Uganda
(BioMed Central, 2009-08-19)
Background: The members of the retinoblastoma protein family, pRb, p107 and pRb2 (p130), are central players in controlling the cell cycle. Whereas disturbed function of pRb is commonly seen in human cancers, it is still ...
MicroRNA Alterations and Associated Aberrant DNA Methylation Patterns across Multiple Sample Types in Oral Squamous Cell Carcinoma
(Public Library of Science, 2011-11-22)
Background: MicroRNA (miRNA) expression is broadly altered in cancer, but few studies have investigated miRNA deregulation in oral squamous cell carcinoma (OSCC). Epigenetic mechanisms are involved in the regulation of ...
Proteogenomic Analysis of Polymorphisms and Gene Annotation Divergences in Prokaryotes using a Clustered Mass Spectrometry-Friendly Database
(American Society for Biochemistry and Molecular Biology, 2011-01)
Precise annotation of genes or open reading frames is still a difficult task that results in divergence even for data generated from the same genomic sequence. This has an impact in further proteomic studies, and also ...