Now showing items 31-40 of 91
Proliferation, lymph vessel invasion and histologic type as prognostic factors in lymph node negative breast cancer
(The University of Bergen, 2011-12-14)
Breast cancer is a leading cause of cancer mortality among women in the western world, second only to lung cancer. Since the mammography screening program in Norway started in 1995, 70% and more of all new breast cancers ...
Secreted proteins and surface markers on tubercle bacilli
(The University of Bergen, 2007-12-12)
Tuberculosis caused by Mycobacterium tuberculosis (M. tuberculosis) is the major cause of mortality and morbidity of over two million people each year. Mapping of proteins exported by the pathogen to the extracellular ...
Uterine cervical neoplasia : aspects of biology and pathology
(The University of Bergen, 2007-01-18)
Patterns of transmitted HIV drug resistance in Europe vary by risk group
Background: In Europe, a continuous programme (SPREAD) has been in place for ten years to study transmission of drug resistant HIV. We analysed time trends of transmitted drug resistance mutations (TDRM) in relation to the ...
Camptothecin and khat (Catha edulis Forsk.) induced distinct cell death phenotypes involving modulation of c-FLIPL, Mcl-1, procaspase-8 and mitochondrial function in acute myeloid leukemia cell lines
(BioMed Central, 2009-11-13)
Background: An organic extract of the recreational herb khat (Catha edulis Forsk.) triggers cell death in various leukemia cell lines in vitro. The chemotherapeutics camptothecin, a plant alkaloid topoisomerase I inhibitor, ...
Evaluation of four novel genetic variants affecting hemoglobin A1c levels in a population-based type 2 diabetes cohort (the HUNT2 study)
(BioMed Central, 2011-02-04)
Background: Chronic hyperglycemia confers increased risk for long-term diabetes-associated complications and repeated hemoglobin A1c (HbA1c) measures are a widely used marker for glycemic control in diabetes treatment and ...
Evaluation of the Sublingual Route for Administration of Influenza H5N1 Virosomes in Combination with the Bacterial Second Messenger c-di-GMP
(Public Library of Science, 2011-11-01)
Avian influenza A H5N1 is a virus with pandemic potential. Mucosal vaccines are attractive as they have the potential to block viruses at the site of entry, thereby preventing both disease and further transmission. The ...
The link between periodontal disease and rheumatoid arthritis: An updated review
Porphyromonas gingivalis is a leading pathogen in chronic periodontitis, a disease process involving progressive destruction of the tissues that support the teeth. Recently, the organism has been reported to produce a ...
Lipocalin 2 expression is associated with aggressive features of endometrial cancer
(BioMed Central, 2012-05-06)
Background: Increased expression of lipocalin 2 (LCN2) has been observed in several cancers. The aim of the present study was to investigate LCN2 in endometrial cancer in relation to clinico-pathologic phenotype, angiogenesis, ...
ERG and SIM2 transcription factors in prostate cancer – their role in carcinogenesis and potential clinical utility
(The University of Bergen, 2011-01-27)