Now showing items 11-20 of 54
The autonomy of different aspects of Sjögren´s syndrome and their treatment in an experimental model: the use of comprehensive biomarker analyses to characterize the disease and the effect of heat-shock proteins in treatment intervention
(The University of Bergen, 2008-06-20)
Sjögren’s syndrome (SS) is a systemic rheumatic disease, in which the salivary and lacrimal glands are the principal targets of a pathological autoimmune reaction. Clinically, SS is manifested by keratoconjunctivitis ...
Benefit from B-Lymphocyte Depletion Using the Anti- CD20 Antibody Rituximab in Chronic Fatigue Syndrome. A Double-Blind and Placebo-Controlled Study
(Public Library of Science, 2011-10-19)
Background: Chronic fatigue syndrome (CFS) is a disease of unknown aetiology. Major CFS symptom relief during cancer chemotherapy in a patient with synchronous CFS and lymphoma spurred a pilot study of B-lymphocyte depletion ...
MicroRNA Alterations and Associated Aberrant DNA Methylation Patterns across Multiple Sample Types in Oral Squamous Cell Carcinoma
(Public Library of Science, 2011-11-22)
Background: MicroRNA (miRNA) expression is broadly altered in cancer, but few studies have investigated miRNA deregulation in oral squamous cell carcinoma (OSCC). Epigenetic mechanisms are involved in the regulation of ...
Interactions between Fusobacterium nucleatum and Primary Human Oral Cells: In Vitro Studies in Monolayer and Organotypic Culture Models
(The University of Bergen, 2012-06-21)
F. nucleatum is a Gram-negative bacterium, member of normal flora in the oral cavity, which has a major role in the formation of the subgingival biofilm. The adhesins expressed on the cell wall outer membrane confer F. ...
Chemokines are secreted by monocytes following OK-432 (lyophilized Streptococcus pyogenes) stimulation
(BioMed Central, 2009-01-28)
Background: OK-432, penicillin-killed Streptococcus pyogenes, is used in treating lymphangiomas and carcinomas. We have studied in vitro the role of mononuclear phagocytes (MNPs), including purified monocytes (MOs), in the ...
Generation of a stepwise prostate carcinogenesis model. A study of epithelial to mesenchymal transition and malignant transformation of prostate primary epithelial cells
(The University of Bergen, 2013-05-29)
Despite progress in recent years, prostate cancer continues to be one of the most prevalent causes of cancer-related mortality and morbidity in men in Western countries. A major clinical challenge of prostate cancer ...
Epidemiological and microbiological aspects of aggressive periodontitis in Sudan
(The University of Bergen, 2012-02-22)
A five-year prospective study of fatigue in primary Sjögren’s syndrome
(BioMed Central, 2011-10-13)
Introduction: Fatigue is prevalent in primary Sjögren’s syndrome (pSS), and contributes to the considerably reduced health related quality of life in this disease. The symptom is included in proposed disease activity ...
Expression of the "stem cell marker" CD133 in pancreas and pancreatic ductal adenocarcinomas
(BioMed Central, 2008-02-08)
Background It has been suggested that a small population of cells with unique self-renewal properties and malignant potential exists in solid tumors. Such "cancer stem cells" have been isolated by flow cytometry, followed ...
Sjögren’s syndrome: studying the disease in mice
(BioMed Central, 2011-06-13)
Sjögren’s syndrome (SS), a systemic autoimmune disease, is characterized by infl ammation of exocrine tissues accompanied by a signifi cant loss of their secretory function. Clinical symptoms develop late and there are ...