Now showing items 1-10 of 20
How participatory is parental consent in low literacy rural settings in low income countries? Lessons learned from a community based study of infants in South India
(BioMed Central, 2011-02-15)
Background A requisite for ethical human subjects research is that participation should be informed and voluntary. Participation during the informed consent process by way of asking questions is an indicator of the extent ...
Treatment-associated polymorphisms in protease are significantly associated with higher viral load and lower CD4 count in newly diagnosed drug-naive HIV-1 infected patients
(BioMed Central, 2012-10-03)
Background: The effect of drug resistance transmission on disease progression in the newly infected patient is not well understood. Major drug resistance mutations severely impair viral fitness in a drug free environment, ...
Proteogenomic Analysis of Polymorphisms and Gene Annotation Divergences in Prokaryotes using a Clustered Mass Spectrometry-Friendly Database
(American Society for Biochemistry and Molecular Biology, 2011-01)
Precise annotation of genes or open reading frames is still a difficult task that results in divergence even for data generated from the same genomic sequence. This has an impact in further proteomic studies, and also ...
Functional analysis of tilS homologues in Bacteria and Archaea
(The University of Bergen, 2005-09-09)
Out of all of the microorganisms sequenced so far about one third of the genes have unknown function. Several studies have shown that information on evolutionary relationships between unknown genes can aid in the prediction ...
Ectopic germinal center formation in Sjögren’s syndrome: Significance of lymphoid organization
(The University of Bergen, 2006-06-23)
Sjögren’s syndrom (SS) is an autoimmune, chronic inflammatory disorder predominantly affecting the salivary and lacrimal glands. The overall aim of this study was to determine clinicopathological features in human and ...
Comprehensive Analysis of Exported Proteins from Mycobacterium tuberculosis H37Rv
(Wiley-VCH Verlag Berlin, 2007-04-21)
Proteins secreted by Mycobacterium tuberculosis play an essential role in the pathogenesis of tuberculosis. The culture filtrates of M. tuberculosis H37Rv made by Sadamu Nagai (Japan), are considerably enriched for secreted ...
Detection and molecular characterization of herpes simplex virus from Tanzania and Norway
(The University of Bergen, 2006-12-22)
ERG and SIM2 transcription factors in prostate cancer – their role in carcinogenesis and potential clinical utility
(The University of Bergen, 2011-01-27)
Secreted proteins and surface markers on tubercle bacilli
(The University of Bergen, 2007-12-12)
Tuberculosis caused by Mycobacterium tuberculosis (M. tuberculosis) is the major cause of mortality and morbidity of over two million people each year. Mapping of proteins exported by the pathogen to the extracellular ...
Counting Mycobacteria in Infected Human Cells and Mouse Tissue: A Comparison between qPCR and CFU
(Public Library of Science, 2012-04-19)
Due to the slow growth rate and pathogenicity of mycobacteria, enumeration by traditional reference methods like colony counting is notoriously time-consuming, inconvenient and biohazardous. Thus, novel methods that rapidly ...