Now showing items 11-20 of 20
Maternal allergen immunisation to prevent sensitisation in offspring: Th2-polarising adjuvants are more efficient than a Th1-polarising adjuvant in mice
(BioMed Central, 2010-03-01)
Background Allergy has been an increasing problem in several parts of the world. Prenatal exposure to allergen and microbial components may affect the development of allergies in childhood, as indicated by epidemiological ...
Age specific aetiological agents of diarrhoea in hospitalized children aged less than five years in Dar es Salaam, Tanzania
(BioMed Central, 2011-02-23)
Background This study aimed to determine the age-specific aetiologic agents of diarrhoea in children aged less than five years. The study also assessed the efficacy of the empiric treatment of childhood diarrhoea using ...
Serodiagnosis of tuberculous lymphadenitis using a combination of antigens
(Open Learning on Enteric Pathogens, 2010)
Background: The diagnosis of extra-pulmonary tuberculosis (EPTB) by conventional methods such as culture and microscopy has low sensitivity and requires an invasive procedure. A simple rapid serological test would be of ...
Herpesviral interactomics. Intraviral and virus-host protein-protein interaction network from different species of herpesviruses
(The University of Bergen, 2008-02-01)
High accuracy mass spectrometry analysis as a tool to verify and improve gene annotation using Mycobacterium tuberculosis as an example
(BioMed Central, 2008-07-02)
Background: While the genomic annotations of diverse lineages of the Mycobacterium tuberculosis complex are available, divergences between gene prediction methods are still a challenge for unbiased protein dataset ...
Comparison of membrane proteins of Mycobacterium tuberculosis H37Rv and H37Ra strains
(BioMed Central, 2011-01-24)
Background: The potential causes for variation in virulence between distinct M. tuberculosis strains are still not fully known. However, differences in protein expression are probably an important factor. In this study ...
CD4 lymphocyte dynamics in Tanzanian pulmonary tuberculosis patients with and without hiv co-infection
(BioMed Central, 2012-03-21)
Background: The interaction of HIV and tuberculosis (TB) on CD4 levels over time is complex and has been divergently reported. Methods: CD4 counts were assessed from time of diagnosis till the end of TB treatment in a ...
Definition of novel cell envelope associated proteins in Triton X-114 extracts of Mycobacterium tuberculosis H37Rv
(BioMed Central, 2010-04-29)
Background Membrane- and membrane-associated proteins are important for the pathogenicity of bacteria. We have analysed the content of these proteins in virulent Mycobacterium tuberculosis H37Rv using Triton X-114 ...
Prevalence of enteropathogenic viruses and molecular characterization of group A rotavirus among children with diarrhea in Dar es Salaam Tanzania
(BioMed Central, 2007-12-27)
Background Different groups of viruses have been shown to be responsible for acute diarrhea among children during their first few years of life. Epidemiological knowledge of viral agents is critical for the development ...
Evidence for waning of latency in a cohort study of tuberculosis
(BioMed Central, 2010-02-23)
Background To investigate how the risk of active tuberculosis disease is influenced by time since original infection and to determine whether the risk of reactivation of tuberculosis increases or decreases with ...