Blar i Department of Biomedicine på emneord "Biomarker"
Viser treff 1-4 av 4
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Androgen receptor as potential therapeutic target in metastatic endometrial cancer
(Peer reviewed; Journal article, 2016-06-30)Purpose: The expression and involvement of estrogen (ER) and progesterone receptor (PR) is extensively studied in endometrial cancer. Androgen receptor (AR) is a hormone receptor less studied in female cancers, and we here ... -
Quantification of the concentration gradient of biomarkers between ovarian carcinoma interstitial fluid and blood
(Peer reviewed; Journal article, 2014-12)Background: Tumor interstitial fluid (TIF) rather than plasma should be used in cancer biomarker discovery because of the anticipated higher concentration of locally produced proteins in the tumor microenvironment. ... -
Serum concentrations of kynurenines in adult patients with attention-deficit hyperactivity disorder (ADHD): a case–control study
(Peer reviewed; Journal article, 2015-11-05)Background: The essential amino acid tryptophan is catabolised mainly through the kynurenine pathway. Altered circulating levels of kynurenines have been reported in chronic inflammatory conditions and in several ... -
Upregulated PDK4 expression is a sensitive marker of increased fatty acid oxidation
(Peer reviewed; Journal article, 2019)Fatty acid oxidation is a central fueling pathway for mitochondrial ATP production. Regulation occurs through multiple nutrient- and energy-sensitive molecular mechanisms. We explored if upregulated mRNA expression of the ...