Now showing items 1-10 of 242
The apoptosis-inducing activity towards leukemia and lymphoma cells in a cyanobacterial culture collection is not associated with mouse bioassay toxicity
Cyanobacteria (83 strains and seven natural populations) were screened for content of apoptosis (cell death)-inducing activity towards neoplastic cells of the immune (jurkat acute T-cell lymphoma) and hematopoetic (acute ...
Visualization of metastatic melanoma cells by fluorescence microscopy and MRI using a novel glycogen nanoprobe
(The University of Bergen, 2014-06-05)
The incidence of malignant melanoma has increased steadily during the last decades. Large portions of individuals with this particular skin cancer develop multiple brain metastases, which is associated with a particular ...
LTP mechanisms in the dentate gyrus in vivo: BDNF signaling, translation control, and gene function
(The University of Bergen, 2007-03-30)
A co-culture model with brain tumor-specific bioluminescence demonstrates astrocyte-induced drug resistance in glioblastoma
(BioMed Central, 2014-10-04)
Background: Although several studies suggest that stromal fibroblasts mediate treatment resistance in several cancer types, little is known about how tumor-associated astrocytes modulate the treatment response in brain ...
Biomedical Image Processing in the Study of Living Cells
(The University of Bergen, 2008-12-09)
Increased plasma colloid osmotic pressure facilitates the uptake of therapeutic macromolecules in a xenograft tumour model
Elevated tumor interstitial fluid pressure (TIFP) is a characteristic of most solid tumors. Clinically, TIFP may hamper the uptake of chemotherapeutic drugs into the tumor tissue reducing their therapeutic efficacy. In ...
The Peripheral Binding of 14-3-3γ to Membranes Involves Isoform-Specific Histidine Residues
(Public Library of Science, 2012-11-26)
Mammalian 14-3-3 protein scaffolds include seven conserved isoforms that bind numerous phosphorylated protein partners and regulate many cellular processes. Some 14-3-3-isoforms, notably γ, have elevated affinity for ...
An eGFP expressing immunodeficent mouse model with dsRED transfected mammary tumours, and the effect of hyperbaric oxygen treatment
(The University of Bergen, 2009-11-20)
Previous studies have shown significant anti-tumour effects of hyperbaric oxygen (HBO) treatment on chemically induced mammary tumours. Thus, to answer whether HBO has a general anti-tumour effect on mammary tumours, the ...
Studies on viral gene transfer and angiogenesis inhibition in experimental glioma models
(The University of Bergen, 2006-11-03)
Autoimmune Addison's Disease and DNA Methylation. Identification of Differentially Methylated Regions and Development of Methylation Specific PCR for Selected Genes
(The University of Bergen, 2012-07-01)
Autoimmune Addison's Disease (AAD) is a classical organ-specific autoimmune disease (AID) that is characterized by autoreactivity towards the adrenal cortex, leading to insufficient production of steroid hormones and ...