Now showing items 1-10 of 221
Investigation of tumour characteristics and treatment strategies in animal models using multiparametric MRI and novel contrast agents
(The University of Bergen, 2007-06-21)
Cellular responses to metabolic stress. A study on the role of mitochondria in the crosstalk between cell metabolism and survival signaling
(The University of Bergen, 2012-08-31)
Metabolic imbalance is associated with increased risk of several diseases, including cancer. Metabolism affects or is affected by virtually all other cellular processes, which is not surprising considering their conserved ...
Role of gingival lymphatics in tissue fluid balance and periodontal disease development
(The University of Bergen, 2012-05-25)
Background: The gingiva is frequently challenged to oral bacteria which are able to induce inflammatory responses with increased fluid filtration and edema formation in the tissue. Under given circumstances periodontal ...
Autoimmune Addison's Disease and DNA Methylation. Identification of Differentially Methylated Regions and Development of Methylation Specific PCR for Selected Genes
(The University of Bergen, 2012-07-01)
Autoimmune Addison's Disease (AAD) is a classical organ-specific autoimmune disease (AID) that is characterized by autoreactivity towards the adrenal cortex, leading to insufficient production of steroid hormones and ...
Phospholipase D in human blood platelets
(The University of Bergen, 2008-05-30)
We have studied phospholipase D (PLD) in human blood platelets. This enzyme hydrolyzes phosphatidylcholine to phosphatidic acid (PA) and choline, where PA is considered to be the main effector of PLDs function in cells. ...
Studies on viral gene transfer and angiogenesis inhibition in experimental glioma models
(The University of Bergen, 2006-11-03)
Abrogation of Anthracycline and Ischemia-Reperfusion Induced Injury by Cell Signaling Modulators
(The University of Bergen, 2013-10-18)
Chemotherapy has a long history in cancer treatment, and the anthracycline used in Paper I and II are among the most effective anti-cancer drugs developed. Unfortunately, the use of anthracyclines is dose-restricted due ...
The Arc of synaptic memory
The immediate early gene Arc is emerging as a versatile, Wnely tuned system capable of coupling changes in neuronal activity patterns to synaptic plasticity, thereby optimizing information storage in the nervous ...
Chronic Consumption of Farmed Salmon Containing Persistent Organic Pollutants Causes Insulin Resistance and Obesity in Mice
(Public Library of Science, 2011-09-23)
Background: Dietary interventions are critical in the prevention of metabolic diseases. Yet, the effects of fatty fish consumption on type 2 diabetes remain unclear. The aim of this study was to investigate whether a diet ...
Cognitive and psychosocial problems in children with epilepsy : a population-based approach
(The University of Bergen, 2007-01-12)