Now showing items 31-40 of 256
Increased plasma colloid osmotic pressure facilitates the uptake of therapeutic macromolecules in a xenograft tumour model
Elevated tumor interstitial fluid pressure (TIFP) is a characteristic of most solid tumors. Clinically, TIFP may hamper the uptake of chemotherapeutic drugs into the tumor tissue reducing their therapeutic efficacy. In ...
The Peripheral Binding of 14-3-3γ to Membranes Involves Isoform-Specific Histidine Residues
(Public Library of Science, 2012-11-26)
Mammalian 14-3-3 protein scaffolds include seven conserved isoforms that bind numerous phosphorylated protein partners and regulate many cellular processes. Some 14-3-3-isoforms, notably γ, have elevated affinity for ...
LTP mechanisms in the dentate gyrus in vivo: BDNF signaling, translation control, and gene function
(The University of Bergen, 2007-03-30)
Design of tumor-specific immunotherapies using dendritic cells - effect of bromelain on dendritic cell maturation
(The University of Bergen, 2009-06-02)
Immunotherapy using dendritic cells (DC) has shown promising results in clinical trials, but few relevant successes are recorded. Therefore, the choice of an appropriate DC population is critical for the outcome of this ...
Exploring and exploiting the potential of pelvic IMRT to spare the bowel
(The University of Bergen, 2011-10-28)
Toxicity and tropism of oncolytic VSV vectors in glioblastoma gene therapy
(The University of Bergen, 2012-11-05)
Glioblastoma multiforme is the most common and most fatal primary brain tumor in adults. Despite using advanced conventional therapeutic approaches like surgical resection, radiotherapy and chemotherapy only marginal ...
Visualization of metastatic melanoma cells by fluorescence microscopy and MRI using a novel glycogen nanoprobe
(The University of Bergen, 2014-06-05)
The incidence of malignant melanoma has increased steadily during the last decades. Large portions of individuals with this particular skin cancer develop multiple brain metastases, which is associated with a particular ...
Reduced Joint Pain after Short-term Duodenal Administration of Seal Oil in Patients with Inflammatory Bowel Disease: Comparison with Soy Oil
(Taylor & Francis, 2004)
Background: Rheumatic joint pain is a common extraintestinal complication of inflammatory bowel disease (IBD). Because the high ratio of n-6 to n-3 fatty acids (FAs) of the Western diet might promote rheumatic disorders, ...
Impact of marine oils in inflammatory bowel disease and psoriatic arthritis. With focus on effects of seal oil and whale oil on joint pain
(The University of Bergen, 2009-09-25)
The Western diet has changed significantly over the last century, e.g. by an increased ratio of omega-6 (n-6) to n-3 polyunsaturated fatty acids (PUFA), particularly due to an increase in the use of vegetable oils like ...
Biomedical Image Processing in the Study of Living Cells
(The University of Bergen, 2008-12-09)