Now showing items 31-40 of 242
The role of autoantibodies in cell mediated autoimmune Addison`s disease
(The University of Bergen, 2012-05-31)
Background: Addison`s disease (primary adrenal insufficiency) is a prototypic organ-specific autoimmune disease affecting the adrenal cortex. Autoimmune Addison`s disease (AAD) is often characterized by autoantibodies ...
Neuronal markers are expressed in human gliomas and NSE knockdown sensitizes glioblastoma cells to radiotherapy and temozolomide
(BioMed Central, 2011-12-20)
Background: Expression of neuronal elements has been identified in various glial tumors, and glioblastomas (GBMs) with neuronal differentiation patterns have reportedly been associated with longer survival. However, the ...
Design of tumor-specific immunotherapies using dendritic cells - effect of bromelain on dendritic cell maturation
(The University of Bergen, 2009-06-02)
Immunotherapy using dendritic cells (DC) has shown promising results in clinical trials, but few relevant successes are recorded. Therefore, the choice of an appropriate DC population is critical for the outcome of this ...
Exploring and exploiting the potential of pelvic IMRT to spare the bowel
(The University of Bergen, 2011-10-28)
Expression of the progenitor marker NG2/CSPG4 predicts poor survival and resistance to ionising radiation in glioblastoma
Glioblastoma (GBM) is a highly aggressive brain tumour, where patients respond poorly to radiotherapy and exhibit dismal survival outcomes. The mechanisms of radioresistance are not completely understood. However, cancer ...
Brain Computer Interface - Neurophysiology and Experimental Examples
(The University of Bergen, 2011-07-20)
The last century has seen an incredible leap in human medicine, which has led to an increased life expectancy spanning over all age groups. Despite this development of modern medicine some patient groups do not have any ...
Biological responses of dental pulp stem cells to surfaces modified by collagen 1 and fibronectin
(The University of Bergen, 2014-01-18)
Collagen 1 and fibronectin are extracellular matrix proteins that contribute in cell activity and involve in regulating dental pulp stem cells. The purpose of this in vitro study was to investigate the effect of collagen ...
Virtual Source Modelling of Photon Beams for Monte Carlo Based Radiation Therapy Treatment Planning
(The University of Bergen, 2011-10-13)
Modern radiotherapy (RT) techniques such as stereotactic body radiotherapy (SBRT), intensitymodulated radiotherapy (IMRT) or volumetric modulated arc therapy (VMAT) carries the potential of improving the quality of ...
Hyperoxia retards growth and induces apoptosis and loss of glands and blood vessels in DMBA-induced rat mammary tumors
(BioMed Central, 2007-01-30)
This study investigated the effects of hyperoxic treatment on growth, angiogenesis, apoptosis, general morphology and gene expression in DMBA-induced rat mammary tumors. Methods: One group of animals was exposed to ...
Function and regulation of phenylalanine and tyrosine hydroxylases from human and Caenorhabditis elegans. With focus in evolutionary aspects and development of new therapies
(The University of Bergen, 2010-06-11)
The family of the aromatic amino acid hydroxylases (AAAH) is well studied in mammals. It includes four members, i.e. phenylalanine hydroxylase (PAH), tyrosine hydroxylase (TH) and the tryptophan hydroxylases (TPH1 and ...