Blar i Department of Biomedicine på forfatter "Aukrust, Pål"

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    • Cardiac Involvement in Systemic and Local Vasculitides: The Value of Noninvasive Multimodality Imaging 

      Mohamed Ali, Abukar; Yakupoglu, H. Yakup; Fuchs, Tobias A.; Larsen, Terje Hjalmar; Aukrust, Pål; Gunnarsson, Ragnar; Saeed, Sahrai (Journal article; Peer reviewed, 2023)
      Despite significant advances in managing systemic vasculitides, cardiovascular morbidity, and mortality are still of primary concern. Advances in noninvasive imaging have broadened our understanding of the clinical ...

    • Instability in NAD+ metabolism leads to impaired cardiac mitochondrial function and communication 

      Lauritzen, Knut H.; Olsen, Maria Belland; Ahmed, Mohammed Shakil; Yang, Kuan; Rinholm, Johanne Egge; Bergersen, Linda H.; Esbensen, Qin Ying; Sverkeli, Lars Jansen; Ziegler, Mathias; Attramadal, Håvard; Halvorsen, Bente; Aukrust, Pål; Yndestad, Arne (Journal article; Peer reviewed, 2021)
      Poly(ADP-ribose) polymerase (PARP) enzymes initiate (mt)DNA repair mechanisms and use nicotinamide adenine dinucleotide (NAD+) as energy source. Prolonged PARP activity can drain cellular NAD+ reserves, leading to de-regulation ...