Blar i Department of Biomedicine på forfatter "Chouaib, Salem"
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AXL Targeting Abrogates Autophagic Flux and Induces Immunogenic Cell Death in Drug-Resistant Cancer Cells
Lotsberg, Maria Lie; Wnuk-Lipinska, Katarzyna; Terry, Stéphane; Tan, Tuan Zea; Lu, Ning; Trachsel-Moncho, Laura; Røsland, Gro Vatne; Siraji, Muntequa Ishtiaq; Hellesøy, Monica; Rayford, Austin James; Jacobsen, Kirstine; Ditzel, Henrik J; Vintermyr, Olav Karsten; Bivona, Trever G; Minna, John; Brekken, Rolf A; Baguley, Bruce; Micklem, David; Akslen, Lars A.; Gausdal, Gro; Simonsen, Anne; Thiery, Jean Paul; Chouaib, Salem; Lorens, James; Engelsen, Agnete (Journal article; Peer reviewed, 2020)Introduction Acquired cancer therapy resistance evolves under selection pressure of immune surveillance and favors mechanisms that promote drug resistance through cell survival and immune evasion. AXL receptor tyrosine ... -
Decoding cancer's camouflage: epithelialmesenchymal plasticity in resistance to immune checkpoint blockade
Lotsberg, Maria Lie; Rayford, Austin James; Thiery, Jean Paul; Bellaggia, Giuliana; Peters, Stacey D'Mello; Lorens, James; Chouaib, Salem; Terry, Stéphane; Engelsen, Agnete (Journal article, 2020)Epithelial-mesenchymal plasticity (EMP) of cancer cells contributes to cancer cell heterogeneity, and it is well established that EMP is a critical determinant of acquired resistance to cancer treatment modalities including ... -
Dissecting the Role of AXL in Cancer Immune Escape and Resistance to Immune Checkpoint Inhibition
Engelsen, Agnete Svendsen Tenfjord; Lotsberg, Maria Lie; Khouzam, Raefa Abou; Thiery, Jean Paul; Lorens, James; Chouaib, Salem; Terry, Stéphane (Journal article; Peer reviewed, 2022)The development and implementation of Immune Checkpoint Inhibitors (ICI) in clinical oncology have significantly improved the survival of a subset of cancer patients with metastatic disease previously considered uniformly ...