Blar i Department of Biomedicine på forfatter "Deng, Lin"
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The dual role of glioma exosomal microRNAs: glioma eliminates tumor suppressor miR-1298-5p via exosomes to promote immunosuppressive effects of MDSCs
Qi, Yanhua; Jin, Chuandi; Qiu, Wei; Zhao, Rongrong; Wang, Shaobo; Li, Boyan; Zhang, Zongpu; Guo, Qindong; Zhang, Shouji; Gao, Zijie; Zhao, Shulin; Pan, Ziwen; Fan, Yang; chen, Zihang; Wang, Huizhi; Xu, Jianye; Deng, Lin; Ni, Shilei; Wang, Jian; Xue, Hao; Xue, Fuzhong; Li, Gang (Journal article; Peer reviewed, 2022)Clear evidence shows that tumors could secrete microRNAs (miRNAs) via exosomes to modulate the tumor microenvironment (TME). However, the mechanisms sorting specific miRNAs into exosomes are still unclear. In order to study ... -
SPI1-induced downregulation of FTO promotes GBM progression by regulating pri-miR-10a processing in an m6A-dependent manner
Zhang, Shouji; Zhao, Shulin; Qi, Yanhua; Li, Boyan; Wang, Huizhi; Pan, Ziwen; Xue, Hao; Jin, Chuandi; Qiu, Wei; Chen, Zihang; Guo, Qindong; Fan, Yang; Xu, Jianye; Gao, Zijie; Wang, Shaobo; Guo, Xing; Deng, Lin; Ni, Shilei; Xue, Fuzhong; Wang, Jian; Zhao, Rongrong; Li, Gang (Journal article; Peer reviewed, 2022)As one of the most common post-transcriptional modifications of mRNAs and noncoding RNAs, N6-methyladenosine (m6A) modification regulates almost every aspect of RNA metabolism. Evidence indicates that dysregulation of m6A ...