Browsing Department of Biomedicine by Author "Ghorbani, Sadaf"
Modelling cellular signal communication mediated by phosphorylation dependent interaction with 14-3-3 proteins Kleppe, Rune; Ghorbani, Sadaf; Martinez, Aurora; Haavik, Jan (ElsevierFederation of European Biochemical Societies, 2014-01-03)The 14-3-3 proteins are important effectors of Ser/Thr phosphorylation in eukaryotic cells. Using mathematical modelling we investigated the roles of these proteins as effectors in signalling pathways that involve ...Journal article
Regulation of tyrosine hydroxylase is preserved across different homo- and heterodimeric 14-3-3 proteins Ghorbani, Sadaf; Fossbakk, Agnete; Jorge Finnigan, Ana; Flydal, Marte Innselset; Haavik, Jan; Kleppe, Rune (Springer, 2016-05)Tyrosine hydroxylase (TH) is regulated by members of the 14-3-3 protein family. However, knowledge about the variation between 14-3-3 proteins in their regulation of TH is still limited. We examined the binding, effects ...Journal article