Now showing items 1-7 of 7

    • Enhanced gene expression from retroviral vectors 

      Blø, Magnus; Micklem, David R.; Lorens, James B. (BioMed Central, 2008-02-25)
      Background: Retroviruses are widely used to transfer genes to mammalian cells efficiently and stably. However, genetic elements required for high-level gene expression are incompatible with standard systems. The retroviral ...
      Journal articlePeer reviewed
    • Expression of the progenitor marker NG2/CSPG4 predicts poor survival and resistance to ionising radiation in glioblastoma 

      Svendsen, Agnete; Verhoeff, Joost J. C.; Immervoll, Heike; Brøgger, Jan C.; Kmiecik, Justyna; Poli, Aurélie; Netland, Inger A.; Planagumà, Jesús; Torsvik, Anja; Sakariassen, Per Øystein; Bjerkvig, Rolf; Enger, Per Øyvind; Tronstad, Karl Johan (Springer, 2011-08-24)
      Glioblastoma (GBM) is a highly aggressive brain tumour, where patients respond poorly to radiotherapy and exhibit dismal survival outcomes. The mechanisms of radioresistance are not completely understood. However, cancer ...
      Peer reviewedJournal article
    • Fibroblast EXT1-Levels Influence Tumor Cell Proliferation and Migration in Composite Spheroids 

      Österholm, Cecilia; Lu, Ning; Lidén, Åsa; Karlsen, Tine V.; Gullberg, Donald; Reed, Rolf K.; Kusche-Gullberg, Marion (Public Library of Science, 2012-07-25)
      Background: Stromal fibroblasts are important determinants of tumor cell behavior. They act to condition the tumor microenvironment, influence tumor growth, support tumor angiogenesis and affect tumor metastasis. Heparan ...
      Peer reviewedJournal article
    • Filamin A binds to CCR2B and regulates its internalization 

      Minsaas, Laura; Planagumà, Jesús; Madziva, Michael; Krakstad, Beate F.; Masià-Balagué, Míriam; Katz, Arieh A.; Aragay, Anna M. (Public Library of Science, 2010-08-17)
      The chemokine (C-C motif) receptor 2B (CCR2B) is one of the two isoforms of the receptor for monocyte chemoattractant protein-1 (CCL2), the major chemoattractant for monocytes, involved in an array of chronic inflammatory ...
      Peer reviewedJournal article
    • Filamin A-Hinge Region 1-EGFP: A Novel Tool for Tracking the Cellular Functions of Filamin A in Real-Time 

      Planagumà, Jesús; Minsaas, Laura; Pons, Mónica; Myhren, Lene Elisabeth; Garrido, Georgina; Aragay, Anna M. (Public Library of Science, 2012-08-01)
      Background: Filamin A (FLNa) is an actin-crosslinking protein necessary for stabilizing the cell surface, organizing protrusive activity and for promoting efficient cellular translocation. Recently, our group demonstrated ...
      Peer reviewedJournal article
    • Hyperoxic Treatment Induces Mesenchymal-to-Epithelial Transition in a Rat Adenocarcinoma Model 

      Moen, Ingrid; Øyan, Anne Margrete; Kalland, Karl-Henning; Tronstad, Karl Johan; Akslen, Lars A.; Chekenya, Martha; Sakariassen, Per Øystein; Reed, Rolf K.; Stuhr, Linda Elin Birkhaug (Public Library of Science, 2009-07-28)
      Tumor hypoxia is relevant for tumor growth, metabolism and epithelial-to-mesenchymal transition (EMT). We report that hyperbaric oxygen (HBO) treatment induced mesenchymal-to-epithelial transition (MET) in a dimetyl-a-b ...
      Journal articlePeer reviewed
    • Proteogenomic Analysis of Polymorphisms and Gene Annotation Divergences in Prokaryotes using a Clustered Mass Spectrometry-Friendly Database 

      De Souza, Gustavo A.; Arntzen, Magnus Øverlie; Fortuin, Suereta; Schürch, Anita; Målen, Hiwa; McEvoy, Christopher R.; Van Soolingen, Dick; Thiede, Bernd; Warren, Robin M.; Wiker, Harald G. (American Society for Biochemistry and Molecular Biology, 2011-01)
      Precise annotation of genes or open reading frames is still a difficult task that results in divergence even for data generated from the same genomic sequence. This has an impact in further proteomic studies, and also ...
      Journal articlePeer reviewed