Browsing Department of Biomedicine by Author "Pelissier, Fanny"
Age-Related Dysfunction in Mechanotransduction Impairs Differentiation of Human Mammary Epithelial Progenitors Pelissier, Fanny; Garbe, James C.; Ananthanarayanan, Badriprasad; Miyano, Masaru; Lin, ChunHan; Jokela, Tiina; Kumar, Sanjay; Stampfer, Martha R.; Lorens, James; LaBarge, Mark A. (Elsevier, 2014-06-26)Dysfunctional progenitor and luminal cells with acquired basal cell properties accumulate during human mammary epithelial aging for reasons not understood. Multipotent progenitors from women aged <30 years were exposed ...Journal article
Pelissier, Fanny; Schapiro, Denis; Chang, Hang; Borowsky, Alexander D.; Lee, Jonathan K.; Parvin, Bahram; Stampfer, Martha R.; LaBarge, Mark A.; Bodenmiller, Bernd; Lorens, James B. (Cell Press, 2018-04)Aging is associated with tissue-level changes in cellular composition that are correlated with increased susceptibility to disease. Aging human mammary tissue shows skewed progenitor cell potency, resulting in diminished ...Journal article
The Role of Age in Cellular Responses to Microenvironmental Cues as a Breast Cancer Susceptibility Factor Pelissier, Fanny (The University of Bergen, 2016-05-09)Aging is the critical risk factor for many forms of cancer. We used the mammary gland as a model system to study the impact of age on human epithelia in which age is the greatest risk factor for cancer. Dysfunctional ...Doctoral thesis