Browsing Department of Biomedicine by Subject "melanoma brain metastasis"
Now showing items 1-2 of 2
In vitro treatment of melanoma brain metastasis by simultaneously targeting the MAPK and PI3K signaling pathways (MDPI, 2014-05-16)Malignant melanoma is the most lethal form of skin cancer, with a high propensity to metastasize to the brain. More than 60% of melanomas have the BRAFV600E mutation, which activates the mitogen-activated protein kinase ...Journal article
A novel nanoprobe for multimodal imaging is effectively incorporated into human melanoma metastatic cell lines (MDPI, 2015-09-08)To facilitate efficient drug delivery to tumor tissue, several nanomaterials have been designed, with combined diagnostic and therapeutic properties. In this work, we carried out fundamental in vitro and in vivo experiments ...Journal article