Blar i Department of Global Public Health and Primary Care på forfatter "Nygård, Ottar"
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Association between gestational hypertension and risk of cardiovascular disease among 617 589 Norwegian women
Riise, Hilde Kristin Refvik; Sulo, Gerhard; Tell, Grethe S.; Igland, Jannicke; Nygård, Ottar; Iversen, Ann-Charlotte; Daltveit, Anne Kjersti (Peer reviewed; Journal article, 2018-05-13)Background: Preeclampsia and gestational hypertension (GH) are the most common hypertensive pregnancy disorders. Preeclampsia has been linked to increased risk of cardiovascular disease (CVD), but a similar association for ... -
Association of dietary vitamin K and risk of coronary heart disease in middle-age adults: the Hordaland Health Study Cohort
Haugsgjerd, Teresa Risan; Egeland, Grace M.; Nygård, Ottar; Vinknes, Kathrine; Sulo, Gerhard; Lysne, Vegard; Igland, Jannicke; Tell, Grethe S. (Journal article; Peer reviewed, 2020)Objective: The role of vitamin K in the regulation of vascular calcification is established. However, the association of dietary vitamins K1 and K2 with risk of coronary heart disease (CHD) is inconclusive. Design: ... -
Associations between disease severity, coping and dimensions of health-related quality of life in patients admitted for elective coronary angiography – a cross sectional study
Ulvik, Bjørg; Nygård, Ottar; Hansestad, Berit H.; Wentzel-Larsen, Tore; Wahl, Astrid K. (Peer reviewed; Journal article, 2008-05-29)Background In patients with suspected coronary artery disease (CAD), the overall aim was to analyse the relationships between disease severity and both mental and physical dimensions of health related quality of life (HRQOL) ... -
Development and validation of a ceramide- and phospholipid-based cardiovascular risk estimation score for coronary artery disease patients.
Hilvo, M; Meikle, PJ; Pedersen, ER; Tell, Grethe S.; Dhar, Indu; Brenner, H; Schöttker, B; Lääperi, M; Kauhanen, D; Koistinen, KM; Jylhä, A; Huynh, K; Mellett, NA; Tonkin, AM; Sullivan, DR; Simes, J; Nestel, P; Koenig, W; Rothenbacher, D; Nygård, Ottar; Laaksonen, R (Peer reviewed; Journal article, 2020)Aims: Distinct ceramide lipids have been shown to predict the risk for cardiovascular disease (CVD) events, especially cardiovascular death. As phospholipids have also been linked with CVD risk, we investigated whether the ... -
Educational inequalities in acute myocardial infarction incidence in Norway: A nationwide cohort study
Igland, Jannicke; Vollset, Stein Emil; Nygård, Ottar; Sulo, Gerhard; Ebbing, Marta; Tell, Grethe Seppola (Peer reviewed; Journal article, 2014-09-04)Background Increasing differences in cardiovascular disease (CVD) mortality across levels of education have been reported in Norway. The aim of the study was to investigate educational inequalities in acute myocardial ... -
Heart Failure Complicating Acute Myocardial Infarction; Burden and Timing of Occurrence: A Nation-wide Analysis Including 86 771 Patients From the Cardiovascular Disease in Norway (CVDNOR) Project
Sulo, Gerhard; Igland, Jannicke; Vollset, Stein Emil; Nygård, Ottar; Ebbing, Marta; Sulo, Enxhela; Egeland, Grace M.; Tell, Grethe Seppola (Peer reviewed; Journal article, 2016)Background: Coronary heart disease (CHD) represents often the underlying conditions for the development of heart failure (HF). We aimed at exploring the burden and timing of HF complicating an acute myocardial infarction ... -
Hypertensive pregnancy disorders increase the risk of maternal cardiovascular disease after adjustment for cardiovascular risk factors
Riise, Hilde Kristin Refvik; Sulo, Gerhard; Tell, Grethe S.; Igland, Jannicke; Egeland, Grace M.; Nygård, Ottar; Selmer, Randi Marie; Iversen, Ann-Charlotte; Daltveit, Anne Kjersti (Peer reviewed; Journal article, 2019)Background and aim: Hypertensive pregnancy disorders are associated with subsequent cardiovascular disease (CVD), but the extent to which this association is explained by shared risk factors is unknown. We aimed to evaluate ... -
Incident coronary heart disease after Preeclampsia: Role of reduced fetal growth, preterm delivery, and parity
Riise, Hilde Kristin Refvik; Sulo, Gerhard; Tell, Grethe S.; Igland, Jannicke; Nygård, Ottar; Vollset, Stein Emil; Iversen, Ann-Charlotte; Austgulen, Rigmor; Daltveit, Anne Kjersti (Peer reviewed; Journal article, 2017)Background: Preeclampsia is a severe pregnancy disorder often complicated by reduced fetal growth or preterm delivery and is associated with long‐term maternal morbidity and mortality. We aimed to assess the association ... -
Intake of carbohydrates and SFA and risk of CHD in middle-age adults: The Hordaland Health Study (HUSK)
Haugsgjerd, Teresa Risan; Egeland, Grace M.; Nygård, Ottar; Igland, Jannicke; Sulo, Gerhard; Lysne, Vegard; Vinknes, Kathrine; Bjørnevik, Kjetil Lauvland; Tell, Grethe S. (Journal article; Peer reviewed, 2020)Objective: Limiting SFA intake may minimise the risk of CHD. However, such reduction often leads to increased intake of carbohydrates. We aimed to evaluate associations and the interplay of carbohydrate and SFA intake on ... -
Interferon-γ–induced inflammatory markers and the risk of cancer: The Hordaland Health Study
Zuo, Hui; Tell, Grethe Seppola; Vollset, Stein Emil; Ueland, Per Magne; Nygård, Ottar; Midttun, Øivind; Meyer, Klaus; Ulvik, Arve; Eussen, Simone (Peer reviewed; Journal article, 2014-06-19)Background It has been reported that interferon-γ (IFN-γ)–induced inflammatory markers, such as circulating neopterin and kynurenine-to-tryptophan ratio (KTR), are increased in patients with cancer and are also a predictor ... -
Markers of vitamin B6 status and metabolism as predictors of incident cancer: The Hordaland Health Study.
Zuo, Hui; Ueland, Per Magne; Eussen, Simone; Tell, Grethe Seppola; Vollset, Stein Emil; Nygård, Ottar; Midttun, Øivind; Meyer, Klaus; Ulvik, Arve (Peer reviewed; Journal article, 2014-11-26)Dietary intake and/or circulating concentrations of vitamin B6 have been associated with risk of cancer, but results are inconsistent and mechanisms uncertain. Pyridoxal 5'-phosphate (PLP) is the most commonly used marker ... -
Neopterin as an effect modifier of the cardiovascular risk predicted by total homocysteine: A prospective 2-cohort study
Bjørnestad, Espen Øglænd; Borsholm, Robert Andre; Svingen, Gard Frodahl Tveitevåg; Pedersen, Eva Ringdal; Seifert, Reinhard; Midttun, Øivind; Ueland, Per Magne; Tell, Grethe S.; Bønaa, Kaare Harald; Nygård, Ottar (Peer reviewed; Journal article, 2017-10)Background: Plasma total homocysteine (tHcy) is related to plasma neopterin, an indicator of interferon‐γ‐mediated immune activation, and both biomarkers positively predict cardiovascular risk. We examined whether the ... -
The PAr index, an indicator reflecting altered vitamin B-6 homeostasis, is associated with long-term risk of stroke in the general population: the Hordaland Health Study (HUSK)
Zuo, Hui; Tell, Grethe S.; Ueland, Per Magne; Nygård, Ottar; Vollset, Stein Emil; Midttun, Øivind; Meyer, Klaus; Ulvik, Arve (Peer reviewed; Journal article, 2018-01)Background: Vitamin B-6 homeostasis is altered during inflammation and immune activation. It is unknown whether altered vitamin B-6 homeostasis is associated with the risk of stroke. Objective: We investigated the relation ... -
Plasma Biomarkers of Inflammation, the Kynurenine Pathway, and Risks of All-Cause, Cancer, and Cardiovascular Disease Mortality. The Hordaland Health Study
Zuo, Hui; Ueland, Per Magne; Ulvik, Arve; Eussen, Simone; Vollset, Stein Emil; Nygård, Ottar; Midttun, Øivind; Theofylaktopoulou, Despoina; Meyer, Klaus; Tell, Grethe Seppola (Peer reviewed; Journal article, 2016)We aimed to evaluate 10 biomarkers related to inflammation and the kynurenine pathway, including neopterin, kynurenine:tryptophan ratio, C-reactive protein, tryptophan, and 6 kynurenines, as potential predictors of all-cause ... -
Plasma concentrations and dietary intakes of choline and betaine in association with atrial fibrillation risk: Results from 3 prospective cohorts with different health profiles
Zuo, Hui; Svingen, Gard Frodahl Tveitevåg; Tell, Grethe S.; Ueland, Per Magne; Vollset, Stein Emil; Pedersen, Eva Ringdal; Ulvik, Arve; Meyer, Klaus; Nordrehaug, Jan Erik; Nilsen, Dennis W.T.; Bønaa, Kaare; Nygård, Ottar (Peer reviewed; Journal article, 2018)Background: Although choline metabolism has been associated with atherosclerotic heart disease, less research attention has been paid to the associations of choline and its oxidative metabolite betaine with cardiac ... -
Plasma methionine, choline, betaine, and dimethylglycine in relation to colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC)
Nitter, Mathilde Hjelle; Norgård, Benedicte Wentzel; De Vogel, Stefan; Eussen, Simone; Meyer, Klaus; Ulvik, Arve; Ueland, Per Magne; Nygård, Ottar; Vollset, Stein Emil; Bjørge, Tone; Tjønneland, Anne; Hansen, Louise; Boutron-Ruault, Marie-Christine; Racine, Antoine; Cottet, Vanessa; Kaaks, Rudolf; Kühn, Tilman; Trichopoulou, Antonia; Bamia, Christina; Naska, Androniki; Grioni, Sara; Palli, Domenico; Panico, Salvatore; Tumino, Rosario; Vineis, Paolo; Bueno-de-Mesquita, H. Bas; Van Kranen, Henk J.; Peeters, Petra H. M.; Weiderpass, Elisabete; Dorronsoro, Miren; Jakszyn, Paula; Sánchez, María-José; Argüelles, Marcial Vicente; Huerta, José-Maria; Barricarte, Aurelio; Johansson, Matthias; Ljuslinder, Ingrid; Khaw, Kay Tee; Wareham, Nicholas J.; Freisling, Heinz; Duarte-Salles, Talita; Stepien, Magdalena; Gunter, Mark J.; Riboli, Élio B. (Peer reviewed; Journal article, 2014-08)Background Disturbances in one carbon metabolism may contribute to carcinogenesis by affecting methylation and synthesis of DNA. Choline and its oxidation product betaine are involved in this metabolism and can serve as ... -
Prognostic Impact of In-Hospital and Postdischarge Heart Failure in Patients With Acute Myocardial Infarction: A Nationwide Analysis Using Data From the Cardiovascular Disease in Norway (CVDNOR) Project
Sulo, Gerhard; Igland, Jannicke; Nygård, Ottar; Vollset, Stein Emil; Ebbing, Marta; Poulter, Neil; Egeland, G.M.; Cerqueira, Charlotte; Jørgensen, Torben; Tell, Grethe S. (Peer reviewed; Journal article, 2017-03)Background: Heart failure (HF) is a serious complication of acute myocardial infarction (AMI). We explored the excess mortality associated with HF as an early or late complication of AMI and describe changes over time in ... -
The risk association of plasma total homocysteine with acute myocardial infarction is modified by serum vitamin A
Olsen, Thomas; Vinknes, Kathrine; Svingen, Gard Frodahl Tveitevåg; Pedersen, Eva Ringdal; Dhar, Indu; Tell, Grethe S.; Blomhoff, Rune; Ueland, Per Magne; Midttun, Øivind; Refsum, Helga; Nygård, Ottar (Peer reviewed; Journal article, 2018)Background. Plasma total homocysteine (tHcy) has been implicated in the development of cardiovascular disease, but the mechanisms remain unclear. Vitamin A (Vit-A) is involved in homocysteine metabolism and we therefore ... -
Smoking and body fat mass in relation to bone mineral density and hip fracture: The Hordaland Health Study
Øyen, Jannike; Gjesdal, Clara Gram; Nygård, Ottar; Lie, Stein Atle; Meyer, Haakon; Apalset, Ellen M.; Ueland, Per Magne; Pedersen, Eva Kristine Ringdal; Midttun, Øivind; Vollset, Stein Emil; Tell, Grethe Seppola (Peer reviewed; Journal article, 2014-03-25)Lower bone mineral density (BMD) in smokers may be attributable to lower body weight or fat mass, rather than to a direct effect of smoking. We analyzed the effects of smoking exposure, assessed by plasma cotinine, and ... -
Smoking, plasma cotinine and risk of atrial fibrillation: the Hordaland Health Study
Zuo, Hui; Nygård, Ottar; Vollset, Stein Emil; Ueland, Per Magne; Ulvik, Arve; Midttun, Øivind; Meyer, Klaus; Igland, Jannicke; Sulo, Gerhard; Tell, Grethe S. (Peer reviewed; Journal article, 2018-01)Background: Cigarette smoking has been identified as a major modifiable risk factor for coronary heart disease and mortality. However, findings on the relationship between smoking and atrial fibrillation (AF) have been ...