Blar i Department of Global Public Health and Primary Care på forfatter "Wiker, Harald G"
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Diagnosis of extrapulmonary tuberculosis using the MPT64 antigen detection test in a high-income low tuberculosis prevalence setting
Hoel, Ida Marie; Sviland, Lisbeth; Syre, Heidi; Dyrhol-Riise, Anne Ma; Skarstein, Ingerid; Jebsen, Peter Wilhelm; Jørstad, Melissa Davidsen; Wiker, Harald G; Mustafa, Tehmina (Journal article; Peer reviewed, 2020)Background Extrapulmonary tuberculosis (EPTB) poses diagnostic challenges due to the paucibacillary nature of the disease. The immunochemistry-based MPT64 antigen detection test (MPT64 test) has shown promising results ... -
Multiplex Analysis of Pro- or Anti-Inflammatory Serum Cytokines and Chemokines in relation to Gender and Age among Tanzanian Tuberculous Lymphadenitis Patients
Mustafa, Tehmina; Brokstad, Karl Albert; Mfinanga, Sayoki Godfrey M.; Wiker, Harald G (Peer reviewed; Journal article, 2015)Objectives. Tuberculous lymphadenitis is the most common formof extrapulmonary tuberculosis (TB) with a female and paediatric preponderance, postulated to be due to differences in the immune response. The aim of this study ... -
Mycobacterial antigens accumulation in foamy macrophages in murine pulmonary tuberculosis lesions: Association with necrosis and making of cavities
Riaz, Syeda Mariam; Bjune, Gunnar Aksel; Wiker, Harald G; Sviland, Lisbeth; Mustafa, Tehmina (Journal article; Peer reviewed, 2020)Understanding mechanisms of cavitation in tuberculosis (TB) is the missing link that could advance the field towards better control of the infection. Descriptions of human TB suggest that postprimary TB begins as lipid ... -
Rapid and Specific Diagnosis of Extrapulmonary Tuberculosis by Immunostaining of Tissues and Aspirates With Anti-MPT64
Purohit, Manju; Sviland, Lisbeth; Wiker, Harald G; Mustafa, Tehmina (Peer reviewed; Journal article, 2017-04)Background: Extrapulmonary tuberculosis (EPTB) constitutes about 15% to 20% of all cases of tuberculosis (TB). The confirmation of EPTB has always been a challenge to laboratory personnel. We aim to evaluate the diagnostic ...