Department of Clinical Medicine
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A human clinical trial using ultrasound and microbubbles to enhance gemcitabine treatment of inoperable pancreatic cancer
(Elsevier, 2016-12)Background: The primary aim of our study was to evaluate the safety and potential toxicity of gemcitabine combined with microbubbles under sonication in inoperable pancreatic cancer patients. The secondary aim was to ...Journal article -
Plasma free choline, betaine and cognitive performance: the Hordaland Health Study
(Cambridge University Press, 2013-02)Choline and betaine are nutrients involved in one-carbon metabolism. Choline is essential for neurodevelopment and brain function. We studied the associations between cognitive function and plasma concentrations of free ...Journal article -
Deformation and initial stability in hip arthroplasty. Effect of neck geometry and fixation – an experimental cadaver study
(The University of Bergen, 2017-06-08)Introduction: The search for and development of the optimal joint implant include preclinical testing. Restoration of the individual and natural biomechanics in the hip joint is a central goal in hip arthroplasty, and ...Doctoral thesis -
Targeted temperature management in cardiac arrest: survival evaluated by propensity score matching
(BioMed Central, 2017)Background: Targeted temperature management in cardiac arrest was introduced following evidence of increased survival from two controlled trials published in 2002. We wanted to investigate whether the introduction of ...Journal article -
Cardiac Arrest in a Community: Epidemiology, Treatment, and Outcome
(The University of Bergen, 2017-09-01)Background: Incidence and mortality from sudden cardiac arrest is high, making it a prevalent cause of death. Both incidence and survival rates show great variability between populations. In order to improve survival ...Doctoral thesis -
Tissue and imaging biomarkers for hypoxia predict poor outcome in endometrial cancer
(Impact Journals, 2016-09-13)Hypoxia is frequent in solid tumors and linked to aggressive phenotypes and therapy resistance. We explored expression patterns of the proposed hypoxia marker HIF-1α in endometrial cancer (EC) and investigate whether ...Journal article -
Defective mitochondrial DNA homeostasis in the substantia nigra in Parkinson disease
(Nature Publishing Group, 2016-11-22)Increased somatic mitochondrial DNA (mtDNA) mutagenesis causes premature aging in mice, and mtDNA damage accumulates in the human brain with aging and neurodegenerative disorders such as Parkinson disease (PD). Here, we ...Journal article -
Diagnostic accuracy of transabdominal ultrasound in chronic pancreatitis
(Elsevier, 2017-04)The performance of transabdominal ultrasound (US) in chronic pancreatitis (CP) following the advances in US technology made during recent decades has not been explored. Our aim in this prospective study was to evaluate the ...Journal article -
Bone cement product and failure in total knee arthroplasty: A follow-up study of 26,147 knee replacements between 1997 and 2013 in Norway
(Taylor & Francis, 2017)Background and purpose — The bone cement market for total knee arthroplasty (TKA) in Norway has been dominated by a few products and distributors. Palacos with gentamicin had a market share exceeding 90% before 2005, ...Journal article -
Elevated microsatellite alterations at selected tetranucleotides in early-stage colorectal cancers with and without high-frequency microsatellite instability: same, same but different?
(Wiley, 2016-07)Microsatellite instability (MSI) is associated with better prognosis in colorectal cancer (CRC). Elevated microsatellite alterations at selected tetranucleotides (EMAST) is a less-understood form of MSI. Here, we aim to ...Journal article -
Clinical patterns of presentation and attenuated inflammatory response in octo- and nonagenarians with perforated gastroduodenal ulcers
(Elsevier, 2016-08)Background. Perforated gastrodudenal ulcer (PGDU) is an operative emergency with high mortality rates. The growing elderly populationincreasingly presents with need for geriatric acute operative care. Current knowledge of ...Journal article -
Brain MR spectroscopy in autism spectrum disorder—the GABA excitatory/inhibitory imbalance theory revisited
(Frontiers, 2015-06-22)Magnetic resonance spectroscopy (MRS) from voxels placed in the left anterior cingulate cortex (ACC) was measured from 14 boys with Autism Spectrum Disorder (ASD) and 24 gender and age-matched typically developing (TD) ...Journal article -
Choline intake and Incidence of Acute Myocardial Infarction in Patients with Stable Angina Pectoris
(The University of Bergen, 2017-06-22)Introduction: Cardiovascular diseases are the leading cause of death worldwide. It can be defined as a group of interrelated diseases of the heart and blood vessels, including atherosclerotic cardiovascular diseases. ...Master thesis -
Assessment of Nutritional Status in Kidney Transplant Patients at Haukeland University Hospital
(The University of Bergen, 2017-06-16)Background and aims: Chronic kidney disease (CKD) may give implications of nutritional status, and studies suggest that patients with CKD have increased risk of malnutrition and nutrition related conditions such as sarcopenia. ...Master thesis -
Pre- and postoperative nutritional status and dietary intake in patients undergoing gastroenterological surgery at St. Olavs Hospital
(The University of Bergen, 2017-06-10)Introduction and aim: The prevalence of malnutrition in hospital ranges between 10%-60%. Patients undergoing gastrointestinal surgery are at risk for malnutrition both because of insufficient food intake pre- and/or ...Master thesis -
"Everyone Needs a Friend Sometimes" - social predictors of long-term remission in first episode psychosis
(Frontiers, 2016-10-04)Background: Predictors of long-term symptomatic remission are crucial to the successful tailoring of treatment in first episode psychosis. There is lack of studies distinguishing the predictive effects of different social ...Journal article -
Cytokine Patterns in Tuberculosis Infection; IL-1ra, IL-2 and IP-10 Differentiate Borderline QuantiFERON-TB Samples from Uninfected Controls
(PLOS, 2016-09-29)Background: Interferon gamma release assays (IGRAs) do not discriminate between active tuberculosis (TB) and latent TB infection (LTBI), which limit their use in TB endemic areas. Subjects with QuantiFERON-TB (QFT) results ...Journal article -
High flow nasal cannula in children: A literature review
(BioMed Central, 2016-07-12)High flow nasal cannula (HFNC) is a relatively new non-invasive ventilation therapy that seems to be well tolerated in children. Recently a marked increase in the use of HFNC has been seen both in paediatric and adult care ...Journal article -
Primary Leiomyosarcoma of the Pancreas—a Case Report and a Comprehensive Review
(Springer, 2016-12)Purpose: Primary mesenchymal tumors of the pancreas are rare, with leiomyosarcomas the most encountered entities among the pancreatic sarcomas. With few exceptions, single case reports published over the last six decades ...Journal article -
Integrin a11 is overexpressed by tumour stroma of head and neck squamous cell carcinoma and correlates positively with alpha smooth muscle actin expression
(Wiley, 2017-04)BACKGROUND: Cancer-associated fibroblasts (CAFs) were shown to be important for tumour progression in head and neck squamous cell carcinomas (HNSCCs). Their heterogeneity and lack of specific markers is increasingly ...Journal article
