Department of Clinical Medicine
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Prognostic relevance of an epigenetic biomarker panel in sentinel lymph nodes from colon cancer patients
(BioMed Central, 2017-09-05)Background: Patients with early colorectal cancer (stages I–II) generally have a good prognosis, but a subgroup of 15–20% experiences relapse and eventually die of disease. Occult metastases have been suggested ...Journal article -
Bariatric surgery reduces fasting total fatty acids and increases n-3 polyunsaturated fatty acids in morbidly obese individuals
(Taylor & Francis, 2017)Background: Obesity is a global pandemic leading to increased mortality and increased risk of cardiovascular disease. Bariatric surgery is an established treatment of obesity leading to weight loss and reduction of mortality. ...Journal article -
Variability of activity patterns across mood disorders and time of day
(BioMed Central, 2017-12-19)Background: Few actigraphy studies in mood disorders have simultaneously included unipolar (UP) and bipolar (BD) depression or BD mixed states as a separate subgroup from mania. This study compared objectively measured ...Journal article -
Graft fixation influences revision risk after ACL reconstruction with hamstring tendon autografts : A study of 38,666 patients from the Scandinavian knee ligament registries 2004–2011
(Taylor & Francis, 2018)Background and purpose — A large number of fi xation methods of hamstring tendon autograft (HT) are available for anterior cruciate ligament reconstruction (ACLR). Some studies report an association between fi xation ...Journal article -
Similar migration in computer-assisted and conventional total knee arthroplasty
(Taylor & Francis, 2017)Background and purpose — Computer-assisted surgery (CAS) in total knee arthroplasty (TKA) has been used in recent years in the hope of improving the alignment and positioning of the implant, thereby achieving a better ...Journal article -
Molecular Subtypes of Breast Cancer: Long-term Incidence Trends and Prognostic Differences
(American Association for Cancer Research, 2016-12)Background: Secular trends in incidence and prognosis of molecular breast cancer subtypes are poorly described. We studied long-term trends in a population of Norwegian women born 1886–1977. Methods: A total of ...Journal article -
FGD5 amplification in breast cancer patients is associated with tumor proliferation and a poorer prognosis
(Springer, 2017-04)Purpose: Proliferation is a hallmark of cancer. Using a combined genomic approach, FGD5 amplification has been identified as a driver of proliferation in Luminal breast cancer. We aimed to describe FGD5 copy number change ...Journal article -
A short endoscopic Secretin test for the diagnosis of chronic pancreatitis
(The University of Bergen, 2018-06-12)Background: The diagnosis of CP is not yet clearly defined. Many national guidelines exist, but - as in many other not clearly defined diseases - there is no worldwide consensus. In CP, evaluation of exocrine pancreatic ...Doctoral thesis -
Cancer-Associated troke: The Bergen NORSTROKE Study
(Karger, 2015-10-13)Background: Underlying malignancy can cause ischemic stroke in some patients. Mechanisms include the affection of the coagulation cascade, tumor mucin secretion, infections and nonbacterial endocarditis. The release of ...Journal article -
Risk factors influencing long-term survival and nursing home placement in stroke survivors and patients with carotid stenosis
(The University of Bergen, 2018-01-11)Risk factors influencing long-term survival and nursing home placement in stroke survivors and patients with carotid stenosis Stroke is one of the leading causes of mortality and morbidity worldwide and one of the most ...Doctoral thesis -
Cancer-Associated Ischemic Stroke: The Bergen NORSTROKE Study
(The University of Bergen, 2018-05-25)Background: Stroke and cancer are both leading causes of death and disability in the Western world. Cancer can lead to a hypercoagulable state that can cause ischemic stroke. Mechanisms include disturbance of the coagulation ...Doctoral thesis -
Bowel function and quality of life after superior mesenteric nerve plexus transection in right colectomy with D3 extended mesenterectomy
(Springer, 2016)Background: The aim of this study was to ascertain the impact of injury to the superior mesenteric nerve plexus caused by right colectomy with D3 extended mesenterectomy as performed in the prospective multicenter trial: ...Journal article -
Evaluation of a guided self-help intervention for irritable bowel syndrome - An interdisciplinary approach
(The University of Bergen, 2017-12-16)Background: Irritable bowel syndrome (IBS) is the most common functional gastrointestinal disorder, defined by recurrent abdominal pain or discomfort, associated with defecation and/or altered bowel habits. Due to the lack ...Master thesis -
Randomized Controlled Trial of Extended Perioperative Counseling in Enhanced Recovery After Colorectal Surgery
(Wolters Kluwer, 2018-06)BACKGROUND: Enhanced recovery after surgery programs reduce the length of hospital stay in patients who undergo elective colorectal resection, but the reasons for this reduction are not well understood. OBJECTIVE: The aim ...Journal article -
Epidemiology of benign external hydrocephalus in Norway - a population-based study
(Elsevier, 2017-08)Background: Benign external hydrocephalus is defined as a rapidly increasing head circumference (occipitofrontal circumference) with characteristic radiological findings of increased subarachnoid cerebrospinal fluid spaces ...Journal article -
C77G in PTPRC (CD45) is no risk allele for ovarian cancer, but associated with less aggressive disease
(PLOS, 2017-07-31)The pan lymphocyte marker CD45 exists in various isoforms arising from alternative splicing of the exons 4, 5 and 6. While naïve T cells express CD45RA translated from an mRNA containing exon 4, exons 4–6 are spliced out ...Journal article -
Type 2 diabetes genes : present status and data from Norwegian studies
(Norsk forening for epidemiologi, 2013)The worldwide rise in prevalence of type 2 diabetes has led to an intense search for the genetic risk factors of this disease. In type 2 diabetes and other complex disorders, multiple genetic and environmental factors, as ...Journal article -
The mediating effect of body mass index on the relationship between smoking and hip or knee replacement due to primary osteoarthritis. A population-based cohort study (the HUNT study)
(PLOS, 2017-12-28)To investigate the total effect of smoking on total hip or knee replacement (THR/TKR) due to primary osteoarthritis (OA) and to quantify the indirect effect of smoking through body mass index (BMI). Participants from the ...Journal article -
The causal role of smoking on the risk of hip or knee replacement due to primary osteoarthritis: a Mendelian randomisation analysis of the HUNT study
(Elsevier, 2017-06)Objective: Smoking has been associated with a reduced risk of hip and knee osteoarthritis (OA) and subsequent joint replacement. The aim of the present study was to assess whether the observed association is likely to be ...Journal article -
Incidence of total hip or knee replacement due to osteoarthritis in relation to thyroid function: a prospective cohort study (The Nord-Trøndelag Health Study)
(BioMed Central, 2017-05-18)Background: To study whether thyroid function was associated with risk of hip or knee replacement due to primary osteoarthritis. Methods: In a prospective cohort study, data from the second and third survey of the ...Journal article
