Blar i Department of Clinical Medicine på utgivelsesdato
Viser treff 1-20 av 2063
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Cognitive assessment in the early stages of multiple sclerosis : the importance of screening and management of cognitive impairment
(Doctoral thesis, 2024-04-19)Bakgrunn: Kognitiv svekkelse er et vanlig symptom hos pasienter med multippel sklerose (MS), med potentielt stor innvirkning på livskvalitet, yrkesdeltagelse og sosialt liv. Dette kan oppstå i alle stadier og alle subtyper ... -
Multiple adversity: Childhood abuse, adult abuse, and perinatal depression in women with multiple sclerosis : A register-based cohort study
(Doctoral thesis, 2024-02-23)Bakgrunn: Stress kan spille en rolle ved multippel sklerose (MS). Stress i barndommen forårsaket av vold og overgrep er assosiert med økt risiko for kroniske sykdommer i voksen alder. Det er ukjent om slikt stress kan ... -
Clinical Management of Vestibular Schwannoma : The V-REX randomized trial and other clinical studies on vestibular schwannoma
(Doctoral thesis, 2024-01-20)Introduksjon: Vestibularis schwannomer (VS) er godartede svulster som utgår fra de Schwannske cellene rundt den åttende hjernenerven og utgjør ca. 8% av alle intrakranielle neoplasmer. Behandlingsalternativene er mikrokirurgisk ... -
Novel biomarkers in multiple sclerosis pathology with a focus on neuroprotection and myelin repair
(Doctoral thesis, 2024-01-16)Multippel sklerose (MS) er en sykdom som fører til skade på nervesystemet, kjennetegnet av definerte områder med vevsskade (lesjoner) i sentralnervesystemet (CNS). Dette resulterer i varig funksjonshemming hos pasienter. ... -
Vestibular Symptoms, Balance and Vestibular Function in Patients with Vestibular Schwannoma
(Doctoral thesis, 2024-01-12)Bakgrunn: Vestibularisschwannom (VS) er en godartet svulst på den 8.hjernenerve som ofte fører til hørselstap, øresus, ustøhet og vertigo. Behandling avhenger av svulstens størrelse og om svulsten vokser, og inkluderer ... -
Potential of AI-Driven Chatbots in Urology: Revolutionizing Patient Care Through Artificial Intelligence
(Journal article; Peer reviewed, 2024)Purpose of Review Artificial intelligence (AI) chatbots have emerged as a potential tool to transform urology by improving patient care and physician efficiency. With an emphasis on their potential advantages and ... -
Prevalence, Risk Factors, and Clinical and Biochemical Characteristics of Alemtuzumab-Induced Graves Disease
(Journal article; Peer reviewed, 2024)Objective Atypical Graves disease (GD) is a common complication in multiple sclerosis (MS) patients treated with alemtuzumab. We present epidemiological, clinical, and biochemical characteristics of alemtuzumab-induced ... -
Impaired glucose utilization in the brain of patients with delirium following hip fracture
(Journal article; Peer reviewed, 2024)Alterations in brain energy metabolism have long been proposed as one of several neurobiological processes contributing to delirium. This is supported by previous findings of altered CSF lactate and neuron-specific enolase ... -
The Delta III and Delta Xtend reverse shoulder arthroplasty. Risk of revision and failure mechanisms: a report on 3,650 cases from the Norwegian Arthroplasty Register 1994-2021
(Journal article; Peer reviewed, 2024)Background The Delta reverse shoulder arthroplasty (RSA) is commonly used worldwide and is the most frequently used RSA in Norway. The aim of this registry-based study was to report 10- and 20-year implant survival, ... -
COL11A1 is associated with developmental dysplasia of the hip and secondary osteoarthritis in the HUNT study
(Journal article; Peer reviewed, 2024)Objective: Developmental dysplasia of the hip (DDH) is a congenital condition affecting 2-3% of all infants. DDH increases the risk of osteoarthritis, is the cause of 30% of all total hip arthroplasties (THAs) in adults ... -
Longer-term quality of care, effectiveness, and cost-effectiveness of implementing a model of care for osteoarthritis: A cluster-randomized controlled trial
(Journal article; Peer reviewed, 2024)Objective: To assess the quality of care, effectiveness, and cost-effectiveness over 12 months after implementing a structured model of care for hip and knee osteoarthritis (OA) in primary healthcare as compared to usual ... -
TP53 mutation and human papilloma virus status as independent prognostic factors in a Norwegian cohort of vulva squamous cell carcinoma
(Journal article; Peer reviewed, 2024)Introduction: Vulva squamous cell carcinoma (VSCC) develops through two separate molecular pathways—one involving high-risk human papilloma virus infection (HPV-associated), and the other without HPV infection (HPV-independent) ... -
“Finding stability”. Experienced and measured function in patients undergoing surgery for patellar instability
(Doctoral thesis, 2023-12-15)Bakgrunn: Vurdering av knefunksjon er helt sentralt for diagnostikk, behandling og oppfølging av pasienter med ulike kneledds lidelser. Derfor er det behov for gyldige og pålitelige måleverktøy, inkludert pasientrapporterte ... -
Patient-reported outcome and fracture-related infection after ankle fracture surgery
(Doctoral thesis, 2023-12-01)Ankelbrudd er det tredje mest vanlige bruddet som opereres etter håndleddsbrudd og hoftebrudd. Disse bruddene utgjør 10% av alle brudd. Operativ behandling er ofte nødvendig for å hindre utvikling av stivhet, smerte og ... -
Breast cancer of the young: Exploring age-related breast cancer biology
(Doctoral thesis, 2023-11-30)Brystkreft er en sykdom som i en økende grad rammer kvinner i Norge og den vestlige verden. Brystkreft blant yngre kvinner er også økende, og dessuten assosiert med mer aggressiv tumor type og verre klinisk utfall sammenlignet ... -
Functional and Prognostic Role of MicroRNAs in Cancer Associated Fibroblasts and Stroma in Oral Squamous Cell Carcinoma
(Doctoral thesis, 2023-11-23)Nyere studier har vist at forandringer i bindevevscellene som omgir kreftsvulsten er viktige for utviklingen av munnhulekreft. Kreft stroma kan regulere fenotypen av kreftcellene, og på den måten kan påvirke klinisk forløpet ... -
Cementing techniques for total knee arthroplasty in Norwegian hospitals; a questionnaire-based study
(Journal article; Peer reviewed, 2023-11-18)Background: Cementing technique in total knee arthroplasty (TKA) may influence implant survival. There is limited knowledge about the results with clinically used techniques. The aim of this study was to investigate ... -
Effect of ADHD Medication on Criminality and Injuries : Quasi-Experimental Evidence for Patients on the Margin of Treatment
(Doctoral thesis, 2023-11-07)Attention-deficit/hyperactivity disorder (ADHD) er den vanligste nevropsykiatriske lidelsen hos barn og unge. Store geografiske variasjoner i diagnostisering og medisinering av ADHD har bidratt til bekymringer om under- ... -
Orthopaedic surgeons' ability to detect pathologic hip fractures: review of 1484 fractures reported to the Norwegian Hip Fracture Register
(Journal article; Peer reviewed, 2023-11-04)Background: The proximal femur is the most common location of metastases in the appendicular skeleton. Data on pathologic hip fractures, however, are sparse despite it is the most frequently operated pathologic fracture. ... -
Syndromic molecular testing in adults hospitalized for suspected community-acquired pneumonia
(Doctoral thesis, 2023-10-26)Den mikrobielle etiologien hos pasienter med samfunnservervet lungebetennelse (CAP) blir ofte ikke avklart på grunn av utilstrekkelige mikrobiologiske metoder og vanskeligheter med å skaffe prøver fra nedre luftveier. Rask ...