Blar i Department of Clinical Medicine på utgivelsesdato
Viser treff 41-60 av 2060
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Radiographic markers of hip dysplasia in young adults: predictive effect of factors in early life
(Journal article; Peer reviewed, 2023-02-11)Background and objectives: Acetabular dysplasia in young adults occurs, despite screening for developmental hip dysplasia (DDH) in the neonatal period. We aimed to examine how early life factors predict radiographic ... -
Biomarkers and risk factors of neurodegeneration in multiple sclerosis
(Doctoral thesis, 2023-02-10)Bakgrunn og mål: Markører på nevrodegenerasjon er tett knyttet til klinisk funksjonsnedsettelse og sykdomsprogresjon hos pasienter med multippel sklerose (MS). Slike biomarkører kan derfor bidra til å identifisere potensielle ... -
Vitamin D, Calcium and Energy intake and the association with bone mineral density among elite level para cyclists and able bodied cyclists
(Master thesis, 2023-01-03)Background: Dietary intakes and supplement use among Paralympic Athletes are generally unknown, and expert advice is scarce. Low bone mineral density (BMD) is an issue many para athletes (PA) meet. Elite cyclists are ... -
Implementing screening for myocardial injury in non-cardiac surgery: perspectives of an ad-hoc interdisciplinary expert group
(Journal article; Peer reviewed, 2023)Objectives. Perioperative myocardial injury (PMI) is increasingly recognised as an important complication of non-cardiac surgery, with often clinically silent presentation, but detrimental prognosis. Active screening for ... -
Histopathological Growth Pattern in Colorectal Liver Metastasis and The Tumor Immune Microenvironment
(Journal article; Peer reviewed, 2023)Almost half of all patients with colorectal cancer present with or eventually develop metastasis, most frequently in the liver. Understanding the histopathological growth patterns and tumor immune microenvironment of ... -
Effects of insufficient sleep on sensorimotor processing in migraine. A randomised, blinded crossover study of event related beta oscillations
(Journal article; Peer reviewed, 2023)Background Migraine has a largely unexplained connection with sleep and is possibly related to a dysfunction of thalamocortical systems and cortical inhibition. In this study we investigate the effect of insufficient sleep ... -
Risk of total hip arthroplasty after elite sport: linking 3304 former world-class athletes with the Norwegian Arthroplasty Register
(Journal article; Peer reviewed, 2023)Objectives: At present, there is no cure for osteoarthritis (OA), but severe hip joint degeneration can require total hip arthroplasty (THA). The literature on OA after elite sport is limited. We hypothesise that elite ... -
Cancer related mortality in multiple sclerosis. A population based cohort study
(Journal article; Peer reviewed, 2023)Background: Cancer is a major cause of death, but how cancer influences mortality risk in Multiple Sclerosis (MS) is unclear. Objectives: Determine all-cause mortality and mortality following a cancer diagnosis among ... -
A Randomised Placebo-Controlled Study of Purified Anthocyanins on Cognition in Individuals at Increased Risk for Dementia
(Journal article; Peer reviewed, 2023)Importance Identifying nutritional compounds which can reduce cognitive decline in older people is a hugely important topic. Objective To study the safety and effect of anthocyanins in maintaining cognitive functioning ... -
What do bereaved relatives of cancer patients dying in hospital want to tell us? Analysis of free-text comments from the International Care of the Dying Evaluation (i-CODE) survey: a mixed methods approach
(Journal article; Peer reviewed, 2023)Purpose We conducted an international survey of bereaved relatives of cancer patients dying in hospitals in seven countries, with the aim to assess and improve the quality of care. The survey used the i-CODE (International ... -
Musculoskeletal pain patterns and association between dizziness symptoms and pain in patients with long term dizziness – a cross-sectional study
(Journal article; Peer reviewed, 2023)Background The impact of long-term dizziness is considerable both on the personal level and in society and may lead to self-imposed restrictions in daily activities and social relations due to fear of triggering the ... -
Dietary fish intake increased the concentration of soluble ACE2 in rats: can fish consumption reduce the risk of COVID-19 infection through interception of SARS-CoV-2 by soluble ACE2?
(Journal article; Peer reviewed, 2023)The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enters the cells after binding to the membrane-bound receptor angiotensin-converting enzyme 2 (ACE2), but this may be prevented through interception by soluble ... -
Paediatric Ureteroscopy (P-URS) reporting checklist: a new tool to aid studies report the essential items on paediatric ureteroscopy for stone disease
(Journal article, 2023)The burden of urolithiasis in children is increasing and this is mirrored by the number of surgical interventions in the form of ureteroscopy (URS). There exist many challenges in performing this surgery for this special ... -
Embryonic Stem Cells Can Generate Oral Epithelia under Matrix Instruction
(Journal article; Peer reviewed, 2023)We aimed to investigate whether molecular clues from the extracellular matrix (ECM) can induce oral epithelial differentiation of pluripotent stem cells. Mouse embryonic stem cells (ESC) of the feeder-independent cell line ... -
Altered transcriptome-proteome coupling indicates aberrant proteostasis in Parkinson's disease
(Journal article; Peer reviewed, 2023)Aberrant proteostasis is thought to be implicated in Parkinson’s disease (PD), but patient-derived evidence is scant. We hypothesized that impaired proteostasis is reflected as altered transcriptome-proteome correlation ... -
Focal adhesion is associated with lithium response in bipolar disorder: evidence from a network-based multi-omics analysis
(Journal article; Peer reviewed, 2023)Lithium (Li) is one of the most effective drugs for treating bipolar disorder (BD), however, there is presently no way to predict response to guide treatment. The aim of this study is to identify functional genes and ... -
The Clinical Frailty Scale for mortality prediction of old acutely admitted intensive care patients: a meta-analysis of individual patient-level data
(Journal article; Peer reviewed, 2023)Background This large-scale analysis pools individual data about the Clinical Frailty Scale (CFS) to predict outcome in the intensive care unit (ICU). Methods A systematic search identified all clinical trials that ... -
Renal Functional Response-Association With Birth Weight and Kidney Volume
(Journal article; Peer reviewed, 2023)Introduction: Renal functional response (RFR) is the acute increase in glomerular filtration rate (GFR) after a protein load. Low RFR is a marker of single nephron hyperfiltration. Low birth weight (LBW) is associated with ... -
Early Diagnosis of Pancreatic Cancer: Clinical Premonitions, Timely Precursor Detection and Increased Curative-Intent Surgery
(Journal article; Peer reviewed, 2023)Background: The overall poor prognosis in pancreatic cancer is related to late clinical detection. Early diagnosis remains a considerable challenge in pancreatic cancer. Unfortunately, the onset of clinical symptoms in ... -
CD47 and CD68 expression in breast cancer is associated with tumor-infiltrating lymphocytes, blood vessel invasion, detection mode, and prognosis
(Journal article; Peer reviewed, 2023)CD47 expressed on tumor cells binds to signal regulatory protein alpha on macrophages, initiating inhibition of phagocytosis. We investigated the relationships between tumor expression of CD47 and CD68 macrophage content, ...