Blar i Department of Clinical Medicine på forfatter "Forthun, Rakel Brendsdal"
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KRAS mutation analysis by droplet digital PCR of duodenal juice from patients with MODY8 and other pancreatic diseases
Choi, Man Hung; Tjora, Erling; Forthun, Rakel Brendsdal; Engjom, Trond; Ræder, Helge; Hovland, Randi; Molven, Anders (Journal article; Peer reviewed, 2021)Background Maturity-onset diabetes of the young type 8 (MODY8 or CEL-MODY) is an inherited pancreatic disease characterized by chronic inflammation of the pancreas and diabetes. It is not known whether MODY8 patients ... -
Novel hybridization- and tag-based error-corrected method for sensitive ctDNA mutation detection using ion semiconductor sequencing
Tjensvoll, Kjersti; Lapin, Morten; Gilje, Bjørnar; Garresori, Herish; Oltedal, Satu; Forthun, Rakel Brendsdal; Molven, Anders; Rozenholc, Yves; Nordgård, Oddmund (Journal article; Peer reviewed, 2022)Circulating tumor DNA (ctDNA) analysis has emerged as a clinically useful tool for cancer diagnostics and treatment monitoring. However, ctDNA detection is complicated by low DNA concentrations and technical challenges. ...