Now showing items 1-10 of 28
Assessment of retention force and bone apposition in two differently coated femoral stems after 6 months of loading in a goat model
(BioMed Central, 2014-08-16)
Background: Since the introduction of uncemented hip implants, there has been a search for the best surface coating to enhance bone apposition in order to improve retention. The surface coating of the different stems ...
Prevalence and implications of elevated microsatellite alterations at selected tetranucleotides in cancer
(Nature Publishing Group, 2014-04-01)
Elevated microsatellite alterations at selected tetranucleotides (EMAST), a variation of microsatellite instability (MSI), has been reported in a variety of malignancies (e.g., neoplasias of the lung, head and neck, ...
What Is the Best Predictor of Mortality in Perforated Peptic Ulcer Disease? A Population-Based, Multivariable Regression Analysis Including Three Clinical Scoring Systems
Background Mortality rates in perforated peptic ulcer (PPU) have remained unchanged. The aim of this study was to compare known clinical factors and three scoring systems (American Society of Anesthesiologists (ASA), Boey ...
Determining universal processes related to best outcome in emergency abdominal surgery: A multicentre, international, prospective cohort study
Introduction: Emergency abdominal surgery outcomes represent an internationally important marker of healthcare quality and capacity. In this study, a novel approach to investigating global surgical outcomes is proposed, ...
Can bone apposition predict the retention force of a femoral stem? An experimental weight-bearing hip-implant model in goats
(BioMed Central, 2015-04-28)
Background: The increasing incidence of prosthesis revision surgery in the Western world has led to an increased focus on the capacity for stem removal. We previously reported on a femoral stem implanted in goats with ...
Predicting outcomes in patients with perforated gastroduodenal ulcers: artificial neural network modelling indicates a highly complex disease
Purpose Mortality prediction models for patients with perforated peptic ulcer (PPU) have not yielded consistent or highly accurate results. Given the complex nature of this disease, which has many non-linear associations ...
Editorial: facts, figures and the future
(BioMed Central, 2015-01-09)
Cellular metabolism in colorectal carcinogenesis: Influence of lifestyle, gut microbiome and metabolic pathways
The interconnectivity between diet, gut microbiota and cell molecular responses is well known; however, only recently has technology allowed the identification of strains of microorganisms harbored in the gastrointestinal ...
Comparison of CpG Island Methylator Phenotype (CIMP) Frequency in Colon Cancer Using Different Probe- and Gene-Specific Scoring Alternatives on Recommended Multi-Gene Panels
Background: In colorectal cancer a distinct subgroup of tumours demonstrate the CpG island methylator phenotype (CIMP). However, a consensus of how to score CIMP is not reached, and variation in definition may influence ...