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Assessment of retention force and bone apposition in two differently coated femoral stems after 6 months of loading in a goat model
(BioMed Central, 2014-08-16)
Background: Since the introduction of uncemented hip implants, there has been a search for the best surface coating to enhance bone apposition in order to improve retention. The surface coating of the different stems ...
Transfusion requirements in septic shock (TRISS) trial - comparing the effects and safety of liberal versus restrictive red blood cell transfusion in septic shock patients in the ICU: protocol for a randomised controlled trial
(BioMed Central, 2013-05-23)
Background: Transfusion of red blood cells (RBC) is recommended in septic shock and the majority of these patients receive RBC transfusion in the intensive care unit (ICU). However, benefit and harm of RBCs have not ...
Developing a novel femoral stem in hip arthroplasty. An innovation process using a weight-bearing animal model
(The University of Bergen, 2015-08-20)
Introduction: To address the growing incidence of hip replacement revision, this project aimed to find a stem that would fulfil three criteria. First, solid osteointegration and long survival of the implant. Second, ...
Stroke volume variation to guide fluid therapy: is it suitable for high-risk surgical patients? A terminated randomized controlled trial
(BioMed Central, 2015-07-22)
Background: Perioperative goal-directed fluid therapy (GDFT) may improve outcome after high-risk surgery. Minimal invasive measurement of stroke volume variation (SVV) has been recommended to guide fluid therapy. We intended ...
Economic aspects of Parkinson’s disease
(The University of Bergen, 2009-11-13)
Background: Next to Alzheimer’s disease, Parkinson’s disease (PD) is the second most neurodegenerative disease. As the population structure in the industrialized and industrializing countries is changing, an increasing ...
Computer Navigation in Total Knee Replacement Surgery. Effect on Outcome
(The University of Bergen, 2013-11-29)
Background: In total knee replacement surgery (TKR), the surgeon aims to align the implant according to the mechanical axis of the limb. Among knee surgeons the dominating belief is that good alignment reduces wear and ...
Survival in Norwegian BRCA1 mutation carriers with breast cancer
(BioMed Central, 2009-04-14)
Several studies of survival in women with BRCA1 mutations have shown either reduced survival or no difference compared to controls. Programmes for early detection and treatment of inherited breast cancer, have failed to ...
Diagnostic, Prognostic and Therapeutic Aspects of Endometrial Stromal Sarcomas, Low Grade and Undifferentiated Endometrial Sarcoma
(The University of Bergen, 2013-06-24)
Paraneoplastic CDR2 and CDR2L antibodies affect Purkinje cell calcium homeostasis
Paraneoplastic cerebellar degeneration (PCD) is characterized by loss of Purkinje cells (PCs) associated with progressive pancerebellar dysfunction in the presence of onconeural Yo antibodies. These antibodies recognize ...
Clock genes and biological rhythms. Effects of psychotropic drugs
(The University of Bergen, 2012-11-16)
The sleep-wake cycle, lipid metabolism and hormone levels are examples of circadian rhythms, which are endogenously generated cycles that reach both maximum and minimum values once in the course of 24 hours. In ...