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Defective i⁶A37 Modification of Mitochondrial and Cytosolic tRNAs Results from Pathogenic Mutations in TRIT1 and Its Substrate tRNA
(PLoS, 2014-06-05)
Identifying the genetic basis for mitochondrial diseases is technically challenging given the size of the mitochondrial proteome and the heterogeneity of disease presentations. Using next-generation exome sequencing, we ...
Does a parental history of cancer moderate the associations between impaired health status in parents and psychosocial problems in teenagers: a HUNT study.
(Wiley, 2014-08)
Severe disease in a parent is associated with increased psychosocial problems in their children. However, moderating factors of such associations are less studied. In this cross-sectional population-based controlled study ...
Womens' opinions on antenatal care in developing countries: results of a study in Cuba, Thailand, Saudi Arabia and Argentina
(BioMed Central, 2003-05-20)
Background:
The results of a qualitative study carried
out in four developing countries (Cuba,
Thailand, Saudi Arabia and Argentina) are presented. The study was conducted in the context of a
randomised controlled trial ...
Effects of dietary guidance on the symptoms, quality of life and habitual dietary intake of patients with irritable bowel syndrome
(Spandidos Publications, 2013-09)
Diet is important in triggering the symptoms of irritable bowel syndrome (IBS). This study investigated the impact of dietary guidance on the symptoms, quality of life and habitual diet of patients with IBS. Forty‑six ...
Assessing medical students’ attitudes towards learning communication skills – which components of attitudes do we measure?
(BioMed Central, 2007-03-30)
Background.
The Communication Skills Attitudes Scale (CSAS) created by Rees, Sheard and Davies and published in 2002 has been a widely used instrument for measuring medical students' attitudes towards learning communication ...
Births in two different delivery units in the same clinic - A prospective study of healthy primiparous women
(BioMed Central, 2009-06-22)
Background: Earlier studies indicate that midwife-led birth settings are associated with modest
benefits, including reduced medical interventions and increased maternal satisfaction. The
generalizability of these studies ...
Short-term outcome of 1,465 computer-navigated primary total knee replacements 2005–2008. A report from the Norwegian Arthroplasty Register
(Informa Healthcare, 2011-06)
Background and purpose: Improvement of positioning and
alignment by the use of computer-assisted surgery (CAS) might
improve longevity and function in total knee replacements, but
there is little evidence. In this study, ...
Serum uri acid: neuroprotection in thrombolysis. The Bergen NORSTROKE study
(BioMed Central, 2011-09-25)
Background: A possible synergic role of serum uric acid (SUA) with thrombolytic therapies is controversial and
needs further investigations. We therefore evaluated association of admission SUA with clinical improvement ...
Proteomic analysis of formalin-fixed paraffin-embedded glomeruli suggests depletion of glomerular filtration barrier proteins in two-kidney one-clip hypertensive rats
(Oxford University Press, 2014-08-16)
Background It is well known that hypertension may cause glomerular damage, but the molecular mechanisms involved are still incompletely understood.
Methods In the present study, we used formalin-fixed paraffin-embedded ...
Gene-Based Analysis of Regionally Enriched Cortical Genes in GWAS Data Sets of Cognitive Traits and Psychiatric Disorders
(PLoS, 2012-02-22)
Background: Despite its estimated high heritability, the genetic architecture leading to differences in cognitive
performance remains poorly understood. Different cortical regions play important roles in normal cognitive ...